不同近视防控手段对脉络膜影响的研究进展  

Research progress on the effects of different myopia prevention and control methods on choroid

作　　者：张尚珠 王佳薇[1] 席瑞洁 柴松[1] Zhang Shangzhu;Wang Jiawei;Xi Ruijie;Chai Song(Department of Ophthalmology,the Second Hospital of Hebei Medical University,Shijiazhuang 050000,Hebei Province,China)

机构地区：[1]河北医科大学第二医院眼科,河北省石家庄市050000

出　　处：《国际眼科杂志》2025年第1期70-75,共6页International Eye Science

摘　　要：我国近视人群呈现高发、低龄化的严峻趋势。许多研究发现近视防控手段如角膜塑形镜、低浓度阿托品滴眼液、光照、后巩膜加固术、中医相关方法等均与脉络膜的厚度、血流及相关分子生物变化有着密不可分的关联。角膜塑形镜和低浓度阿托品具有脉络膜增厚效应、脉络膜血流调控作用;配戴多点离焦防控镜具有脉络膜增厚效应;光照和哺光仪的近视防控效果在脉络膜厚度和血流上的作用也有体现;中医方法的近视防控效果体现在脉络膜微结构的改变上,但有关各种防控手段对脉络膜的远期影响仍需大样本量研究探索。文章对脉络膜与近视防控手段的关联进行综述,以说明防控手段在脉络膜层面防控近视的原理,以期对临床发现新的防控手段提供新的思路。In recent years,there has been a significant surge in the prevalence of myopia at younger ages in China.Numerous studies have investigated methods for preventing and controlling myopia,including orthokeratology,low-concentration atropine eye drops,light therapy,posterior scleral reinforcement,and traditional Chinese medicine.These approaches can modulate choroidal thickness,blood flow,and target various molecular mechanisms.Orthokeratology and low-concentration atropine demonstrate a thickening effect on the choroid and regulate choroidal blood flow;the use of multi-point defocus control lenses also shows promise in thickening the choroid;the influence of light and light feeding therapy on myopia prevention and control is also reflected in the choroidal thickness and blood flow;and the traditional Chinese medicine has shown good prospect in influencing the microstructure of the choroid for myopia prevention and control.However,the long-term effects of various prevention and control measures on the choroid still need to be explored with a large sample size.This article provides an overview of various methods used to regulate the choroid and prevent myopia.The mechanisms by which these interventions act on the choroid are described to provide new insights and identity novel clinical strategies for myopia management.

关 键 词：脉络膜厚度 脉络膜血流 近视防控 

分 类 号：R778.11[医药卫生—眼科]