不同屈光度青少年近视患者配戴角膜塑形镜的疗效分析  

Efficacy of orthokeratology lenses in adolescent myopia patients with different diopters

作　　者：李小静 伍玲玲 杨倩倩 赵森 刘云 孟瓅 Li Xiaojing;Wu Lingling;Yang Qianqian;Zhao Sen;Liu Yun;Meng Li(Xianyang Aier Eye Hospital,Xianyang 712000,Shaanxi Province,China;Xi'an Aier Ancient City Eye Hospital,Xi'an 710061,Shaanxi Province,China)

机构地区：[1]咸阳爱尔眼科医院,陕西省咸阳市712000 [2]西安古城爱尔眼科医院,陕西省西安市710061

出　　处：《国际眼科杂志》2025年第1期162-165,共4页International Eye Science

摘　　要：目的:探讨不同屈光度青少年近视患者配戴角膜塑形镜1 a的控制效果。方法:采用前瞻性非随机对照研究。收集2022-11/2023-05在我院视光科验配角膜塑形镜的青少年近视患者120例224眼,平均年龄11.00±2.08岁,根据等效球镜度分为3组:其中-0.50--2.00 D组86眼,-2.25--4.00 D组99眼,-4.25--6.00 D组39眼。随访1 a,观察三组患者戴镜前及戴镜1 a后裸眼视力、眼轴、角膜曲率、角膜中央厚度及角膜内皮细胞密度的变化情况。结果:共113例212眼完成1 a随访,其中-0.50--2.00 D组82眼,-2.25--4.00 D组95眼,-4.25--6.00 D组35眼。戴镜1 a后,三组患者角膜中央厚度、角膜内皮细胞密度较戴镜前无差异(均P>0.05),裸眼视力较戴镜前均显著提高,角膜水平曲率(平K值)及角膜垂直曲率(陡K值)均明显变平坦(均P<0.01)。戴镜1 a后三组患者眼轴增长量分别为0.21±0.26、0.13±0.21和0.09±0.10 mm(P<0.05),-0.50--2.00 D组与-2.25--4.00 D组、-4.25--6.00 D组比较均有差异(P=0.028、0.010),-2.25--4.00 D组与-4.25--6.00 D组比较无差异(P=0.344)。结论:青少年近视患者配戴角膜塑形镜安全有效,能预防眼轴非良性增长、有效延缓近视发展,尤其对-2.0 D以上近视患者的眼轴控制更好,近视控制效果更佳。·AIM:To explore the control effects of wearing orthokeratology lens for 1 a on adolescent myopia patients with different diopters.·METHODS:Prospective non-randomized controlled study.A total of 120 adolescent myopic patients(224 eyes),with an average age of 11.00±2.08 years old,who were fitted with orthokeratology lenses in the optometry department of our hospital from November 2022 to May 2023 were collected.There were 3 groups according to the spherical equivalent,including 86 eyes in the group of-0.50--2.00 D,99 eyes in the group-2.25--4.00 D,and 39 eyes in group-4.25--6.00 D.Patients were followed up for 1 a to observe the changes of uncorrected visual acuity,axial length,corneal curvature,corneal central thickness and corneal endothelial cells density in the three groups after wearing lens for 1 a.·RESULTS:A total of 113 cases(212 eyes) were followed up for 1 a,including 82 eyes in the group of-0.50--2.00 D,95 eyes in the group of-2.25--4.00 D,and 35 eyes in the group of-4.25--6.00 D.There was no statistical difference in corneal central thickness and corneal endothelial cell density among the three groups of patients after wearing lens for 1 a(all P>0.05).Uncorrected visual acuity was significantly improved,and flat kerotometry(FK) and steep kerotometry(SK) were significantly flatter(both P<0.01).Furthermore,the growth of axial length in the three groups of patients after wearing lens for 1 a was 0.21±0.26,0.13±0.21 and 0.09±0.10 mm,respectively(P<0.05).There were differences between the-0.50--2.00 D group and the-2.25--4.00 D group and-4.25--6.00 D group(P=0.028,0.010),and there were no differences between the-2.25--4.00 D group and the-4.25--6.00 D group(P=0.344).·CONCLUSION:It is safe and effective for young myopia patients to wear orthokeratology lenses,which can prevent the non-benign growth of the axial length and effectively delay the development of myopia,and the myopia control effect is better especially for myopia patients of above-2.0 D.

关 键 词：角膜塑形镜 近视 眼轴 疗效分析 

分 类 号：R778.11[医药卫生—眼科]