Effect of three-week exercise program on muscle strength and joint mobility in patients with diabetic polyneuropathy:Randomized controlled trial  

作　　者：Snježana Novaković-Bursać Goran Talić Nataša Tomić RankoŠkrbić Ivan Soldatovic 

机构地区：[1]Management,Institute for Physical Medicine,Rehabilitation and Orthopedic Surgery“Dr Miroslav Zotović”Banja Luka,Banja Luka 78000,Republika Srpska,Bosnia and Herzegovina [2]Centre for Biomedical Research,Faculty of Medicine,University of Banja Luka,Banja Luka 78000,Republika Srpska,Bosnia and Herzegovina [3]Institute of Medical Statistics and Informatic,Faculty of Medicine,University of Belgrade,Belgrade 11000,Serbia

出　　处：《World Journal of Diabetes》2024年第12期2311-2321,共11页世界糖尿病杂志（英文）

摘　　要：BACKGROUND Limited joint mobility is the proven risk factor for diabetic foot ulceration when present in the subtalar and first metatarsophalangeal joints.Evidence shows that a foot-related exercise program,combined with a health-promoting program,can improve the signs and symptoms of diabetic polyneuropathy,enhance gait,res-tore mobility in the foot and ankle joints,redistribute pressure while walking,and increase foot strength and function.As a result,these exercise programs can help mitigate the risk factors for diabetic foot ulceration.AIM To determine the effect of supervised stretching,strengthening,functional and walking exercises on joint mobility and muscle strength in patients with diabetic polyneuropathy.METHODS This was a randomized controlled trial conducted in a tertiary hospital.The study included 82 participants allocated into the intervention group(alpha-lipoic acid and exercise on 15 consecutive therapeutic days,n=42)and control group(alpha lipoic acid only,n=40).Muscle strength included dorsal and plantar flexors dynamometry and strength score,while range of motion included ankle,subtalar and first metatarsophalangeal joint goniometry.RESULTS Change of motion range was significantly higher in the intervention group compared to the control group regarding ankle joint on day 15(9.9±7.2 vs 0.1±3.3;P=0.006)and month 6(2.8±7.3 vs-0.9±4.1;P<0.001),subtalar joint on day 15(7.5±5.1 vs-0.25±2.25;P<0.001)and month 6(3.9±6.4 vs-0.13±3.49;P<0.001).Change in dorsal flexors was significantly higher in the intervention group compared to the control group on day 15(2.62±1.69 vs 0.10±1.35;P<0.001)and month 6(0.66±2.38 vs-0.75±1.94;P=0.004)as well as plantar flexors on day 15(3.3±1.6 vs 0.3±1.5;P<0.001)and month 6(1.8±2.2 vs-0.9±2.1;P<0.001).Muscle strength score change was significantly lower in the intervention group compared to the control group on day 15(-1.45±1.42 vs-0.03±0.16;P<0.001)and month 6(-1.17±1.53 vs 0.20±0.56;P<0.001).CONCLUSION Exercise in combination with alpha-lipoic acid c

关 键 词：DIABETES Diabetic polyneuropathy Diabetic foot ulcer Muscle strength Range of motion EXERCISE 

分 类 号：R587.1[医药卫生—内分泌]