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机构地区:[1]Department of Endocrinology&Metabolism,West China Hospital,Sichuan University,Chengdu 610041,Sichuan Province,China [2]Innovation Research Center for Diabetic Foot,Diabetic Foot Care Center,West China Hospital,Sichuan University,Chengdu 610041,Sichuan Province,China
出 处:《World Journal of Diabetes》2024年第12期2384-2386,共3页世界糖尿病杂志(英文)
基 金:Supported by the Health Commission of Sichuan Province,No.23LCYJ042;the Science and Technology Bureau of Sichuan Province,No.2021JDKP004;a Research Grant Investigating the Effect and Mechanism of Secretory Components Derived from Umbilical Cord Mesenchymal Stem Cells on Chronic Wound Healing in Bama Miniature Pig with Diabetes,No.HX-H2206155.
摘 要:In this paper,we provide a commentary on an article focusing on diabetic foot ulcer(DFU)as a dreadful complication of diabetes mellitus.The development of this condition is influenced by factors such as diabetic peripheral neuropathy,lower extremity artery disease,and infection.However,the underlying mecha-nism remains elusive.Macrophages play a critical role in wound healing proce-sses,suggesting that therapies targeting these cells could potentially improve the management of DFU.A comprehensive understanding of developmental trends of macrophages within the field of DFU may facilitate research advancements and the development of novel treatment strategies.
关 键 词:Diabetic foot ulcer MACROPHAGES Immune regulation Wound healing BIBLIOMETRICS
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