Exploring the current provision of pancreatic transplantations in lowand middle-income countries:Current landscape,challenges,future prospects  

作　　者：Hareesha Rishab Bharadwaj Joecelyn Kirani Tan Syed Hasham Ali Muhammad Hamza Shah Aderinto Nicholas Khabab Abbasher Hussien Mohamed Ahmed Khansa Irfan Priyal Dalal Aashna Mehta Wireko Andrew Awuah Arkadeep Dhali 

机构地区：[1]Faculty of Biology Medicine and Health,University of Manchester,Manchester M139PL,United Kingdom [2]Faculty of Medicine,University of St Andrews,St Andrews KY169AJ,United Kingdom [3]Faculty of Medicine,Dow Medical College,Karachi 74200,Pakistan [4]School of Medicine,Queen's University Belfast,Belfast BT71NN,United Kingdom [5]Department of Medicine and Surgery,Ladoke Akintola University of Technology,Ogbomosho 210214,Oyo,Nigeria [6]Faculty of Medicine,University of Khartoum,Khartoum 0000,Sudan [7]School of Medicine,University of Central Lancashire,Preston PR21SG,United Kingdom [8]Faculty of Medicine and Surgery,University of Debrecen,Debrecen 4032,Hungary [9]Faculty of Medicine and Surgery,Sumy State University,Sumy 40007,Ukraine [10]Department of Gastroenterology,Sheffield Teaching Hospitals NHS Foundation Trust,Royal Hallamshire Hospital,Sheffield S102JF,United Kingdom [11]School of Medicine and Population Health,University of Sheffield,Sheffield S102HQ,United Kingdom [12]Deanery of Clinical Sciences,The University of Edinburgh,Edinburgh EH164SB,United Kingdom [13]Leeds Institute of Health Sciences,University of Leeds,Leeds LS29LN,United Kingdom

出　　处：《World Journal of Gastrointestinal Pathophysiology》2024年第6期1-10,共10页世界胃肠病理生理学杂志（英文）

摘　　要：This comprehensive review addresses the global health challenge of disparities in pancreas transplant access,particularly in low-and middle-income countries(LMICs)compared to high-income countries.Despite advancements in surgical techniques and immunosuppression for procedures like simultaneous pancreas-kidney,pancreas-after-kidney,and pancreas-transplant alone,LMICs face significant challenges,including limited infrastructure,financial constraints,and a shortage of skilled medical professionals.Donation after brain death remains constrained by sociocultural barriers.Region-specific analyses highlight progress in Latin America,Asia,Russia,and South Africa,showcasing the regional disparities in access and outcomes.Future prospects involve minimally invasive surgeries,telemedicine for enhanced post-operative care,international collaborations with organizations like the European Union of Medical Specialists,and robust funding networks to improve organ availability.In conclusion,the review underscores the importance of multifaceted strategies to address economic,sociocultural,and infrastructural barriers,aiming to improve accessibility,quality,and effectiveness of pancreas transplantation services in LMICs.

关 键 词：Pancreatic transplantation Diabetes mellitus Global health Low-and middle-income countries Transplant surgery 

分 类 号：R735[医药卫生—肿瘤]