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作 者:Xian-Rong Wu Xiao-Hong He Yong-Fang Xie
出 处:《World Journal of Gastrointestinal Oncology》2025年第1期13-21,共9页世界胃肠肿瘤学杂志(英文)
摘 要:This editorial,inspired by a recent study published in the World Journal of Gastrointestinal Oncology,covers the research findings on microbiota changes in various diseases.In recurrent colorectal polyps,the abundances of Klebsiella,Parvimonas,and Clostridium increase,while those of Bifidobacterium and Lactoba-cillus decrease.This dysbiosis may promote the formation and recurrence of polyps.Similar microbial changes have also been observed in colorectal cancer,inflammatory bowel disease,autism spectrum disorder,and metabolic syndrome,indicating the role of increased pathogens and decreased probiotics in these conditions.Regulating the gut microbiota,particularly by increasing probiotic levels,may help prevent polyp recurrence and promote gut health.This microbial intervention strategy holds promise as an adjunctive treatment for patients with colorectal polyps.
关 键 词:Recurrent colorectal polyps Gut microbiota dysbiosis KLEBSIELLA PROBIOTICS Intestinal inflammation Microbial intervention strategy
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