Recurrent oropharyngeal cancer: Analysis of surgical treatment outcomes  

作　　者：Konstantin Ilkaev Shalva R Gvetadze Ekaterina A Roshchina Ruben I Azizyan Ali M Mudunov Mikhail V Bolotin Xin Yang Denis Larinov 

机构地区：[1]Head and Neck Cancer Surgery and Oncology Department,NN Blokhin National Medical Research Center of Oncology,Moscow 115478,Moskva,Russia [2]Department of Out-Patient,PA Hertzen Moscow Oncology Research Institute-branch of the National Medical Research Radiological Center,Moscow 125284,Moskva,Russia [3]Department of Surgical Oncology,Russian Scientific Center of Roentgenoradiology,Moscow 117997,Moskva,Russia [4]Department of Emergency,University of Mississippi Medical Centre,Jackson,MS 3921,United States [5]Department of Oncology,Sechenov First Moscow State Medical University,Moscow 119048,Moskva,Russia [6]Head&Neck Oncology,NN Blokhin National Medical Research Center of Oncology,Moscow 115478,Moskva,Russia [7]Department of Oral and Maxillofacial-Head and Neck Oncology,Hanghai Key Laboratory of Stomatology&Shanghai Research Institute of Stomatology,National Clinical Center for Oral Disease,Shanghai Ninth People's Hospital,Shanghai Jiao Tong University School of Medicine,Shanghai 200011,China [8]Radiation Oncology Department,Advanced Care Oncology Center,Dubai 214630,Dubai,United Arab Emirates

出　　处：《World Journal of Otorhinolaryngology》2024年第3期25-32,共8页世界耳鼻咽喉科杂志（英文）

摘　　要：BACKGROUND The main goal of our research is to introduce transoral robotic surgery and laser resection(TLR)as a considerable way of treating patients with recurrent oropha-ryngeal malignancies.AIM To develop a foundation of minimally invasive transoral surgical technique for patients with oropharyngeal recurrence.METHODS This study prospectively and retrospectively included patients with recurrent tumors from 2003 to 2018.Subjects were allocated into two groups:(1)Group I;underwent TLR;and(2)Group II(control);underwent open surgeries of varying volume.Evaluation was done with intraoperative blood loss,postoperative infection incidence,and quality of life using the scale for patients with head and neck tumors known as the Functional Assessment of Cancer Therapy-Head&Neck Scale.RESULTS One-hundred and forty one patients were included(103 males and 38 females),in 82 cases(85.4%),a recurrent tumor developed earlier than a year after primary tumor therapy;forty-six were in group I and 69 in group II,age ranging from 18 years to 86 years(average:57.6 years).The first group showed a statistically significant less amount of blood loss and a decreased incidence of infectious complications(P<0.05).Additionally,there was a significant difference in functional outcomes(quality of life scores)but no significant difference in survival curves.CONCLUSION In properly elected patients,TLR is not just reasonable but tends to be a favorable alternative for recurrent oropharyngeal cancers compared to the outcomes of the open surgery group.

关 键 词：Oropharyngeal cancer Transoral laser resection Open surgery Recurrent tumor Oropharyngeal squamous cell carcinoma 

分 类 号：R739.85[医药卫生—肿瘤]