Herpes simplex virus 2-induced aseptic meningitis presenting with sudden deafness:A case report  

作　　者：Yuan-Cheng Liu Shih-Hsuan Hsiao Peir-Rong Chen 

机构地区：[1]Department of Otolaryngology,Hualien Tzu Chi Hospital,Hualien 970,Taiwan,China [2]Department of Otolaryngology,Hualien Tzu Chi Hospital,and Department of Otolaryngology,Head and Neck Surgery,School of Medicine,Tzu Chi University,Hualien 970,Taiwan,China

出　　处：《World Journal of Clinical Cases》2025年第8期22-25,共4页世界临床病例杂志（英文）

摘　　要：BACKGROUND Aseptic meningitis is defined as meningeal inflammation caused by various etio-logies with negative cerebrospinal fluid(CSF)bacterial culture.The most common etiologies are viruses[enteroviruses,arboviruses,and herpes simplex virus type 2(HSV-2)].Aseptic meningitis can have various presentations,including sensori-neural deafness.While sensorineural deafness from mumps meningoencephalitis has been reported,cases of HSV-2-induced hearing loss are rare.Herein,we re-port a case of HSV-2-induced meningitis that presented with sudden deafness.CASE SUMMARY A 68-year-old man experienced a profound sudden onset of left-sided hearing loss for one day.Pure-tone audiograms demonstrated sudden left-sided sensorineural hearing loss(thresholds 80-90 dB).After treatment with high-dose steroids for 1 week,he experienced an acute consciousness change with left hemiparesis.The laboratory data showed no significant abnormalities.Brain computed tomography without contrast and magnetic resonance imaging revealed no intracranial hemo-rrhage or obvious brain lesion.The CSF analysis and the Multiplex PCR panels showed HSV-2 positivity.Hence,under the diagnosis of herpes meningoenceph-alitis,acyclovir was prescribed and his symptoms gradually resolved.CONCLUSION This case report further demonstrates that a viral infection could be a cause of sudden sensorineural hearing loss.

关 键 词：Aseptic meningitis Type 2 herpes simplex Sudden sensorineural hearing loss IMMUNOCOMPROMISED Cerebrospinal fluid Case report 

分 类 号：R743.3[医药卫生—神经病学与精神病学]