术前螺旋CT多参数联合评估肝癌微血管浸润的价值研究  

The Value of Multiparametric Combined Preoperative Assessment of Microvascular Invasion in Small HCC Using Spiral Computed Tomography

作　　者：张成芳[1] 陈晓琼[2] 聂新民[3] 范磊[1] ZHANG Cheng-fang;CHEN Xiao-qiong;NIE Xin-min;Fan Lei(Department of Radiology,The First Hospital of Hunan University of Chinese Medicine,Changsha 410007,Hunan Province,China;Department of Ultrasound Imaging,The First Hospital of Hunan University of Chinese Medicine,Changsha 410007,Hunan Province,China;Department of Laboratory Medicine,The Third Xiangya Hospital of Central South University,Changsha 410015,Hunan Province,China)

机构地区：[1]湖南中医药大学第一附属医院放射科,湖南长沙410007 [2]湖南中医药大学第一附属医院超声影像科,湖南长沙410007 [3]中南大学湘雅三医院检验科,湖南长沙410015

出　　处：《中国CT和MRI杂志》2024年第12期101-102,共2页Chinese Journal of CT and MRI

基　　金：湖南省重点研发计划(2021-2022年)项目(2022SK2004)。

摘　　要：目的探究多层螺旋CT(multi-slice spiral CT,MSCT)在预测肝细胞癌(hepatocellular carcinoma,HCC)微血管浸润中的应用价值。方法本研究对2020年7月至2022年7月间,本院收治的102名肝细胞癌患者的CT图像资料与临床记录进行了回溯分析。根据患者病理诊断,将其分为微血管浸润组与无非血管浸润组。采用独立样本t检验,比较了两组患者的年龄、甲胎蛋白(AFP)浓度、肿瘤大小及增强程度。此外,通过χ^(2)检验分析了性别、肝炎类别、肝功能等级、肿瘤分化状况、肿瘤表面形态、包膜完整性及邻近强化特征等变量。结果102名患者中,52名未观察到微血管浸润,而另50名确认有微血管浸润。分析指出,肿瘤的大小、分化级别、边界特性、包膜状况、门静脉CT值以及周围强化模式与微血管浸润存在显著关联。结论多层螺旋CT的术前影像学特征对于预判肝细胞癌的微血管浸润具有重要的参考意义。Objective To investigate the value of multi slice spiral CT(MSCT)in predicting microvascular invasion in hepatocellular carcinoma(HCC).MethodsThe CT and clinical data of 102 hepatocellular carcinoma patients treated in our hospital from July 2020 to July 2022 were retrospectively reviewed.It was divided into microvascular invasion group and no microvascular invasion group according to the pathological findings.Independent samples t-tests were used to compare age,alpha fetoprotein(AFP)values,tumor size,and tumor enhancement between the two groups.useχ-Theχ^(2)test was used to compare gender,hepatitis type,liver function grade,grade,tumor smoothness,capsule,and peripheral enhancement between the two groups.ResultsThere were 52 cases of non microvascular invasion and 50 cases of microvascular invasion.Tumor size,grade,margin extent,encasement,portal vein CT values,and peripheral enhancement were associated with microvascular invasion.Conclusion MSCT preoperative performance predicts microvascular invasion in hepatocellular carcinoma.

关 键 词：多层螺旋CT 肝细胞癌 微血管侵犯 

分 类 号：R575[医药卫生—消化系统]