肌钙蛋白与BNP监测在预测神经外科脑动脉瘤破裂出血预后中的作用分析  

Analysis of the role of troponin and BNP monitoring in predicting the prognosis of cerebral aneurysm rupture and hemorrhage in neurosurgery

作　　者：刘琼 黄瑞宏[1] 李凯 LIU Qiong;HUANG Ruihong;LI Kai(Sanming Second Hospital,Sanming 366000,China)

机构地区：[1]三明市第二医院,福建三明366000

出　　处：《延边大学医学学报》2024年第4期400-403,共4页Journal of Medical Science Yanbian University

摘　　要：目的:本研究旨在分析肌钙蛋白与脑利钠肽(BNP)监测在预测神经外科脑动脉瘤破裂出血预后中的作用。方法:回顾性分析2017年1月至2023年9月三明市第二医院收治的脑动脉瘤破裂出血患者的临床数据,根据预后情况将患者分为观察组(预后良好)和对照组(预后不良)。比较两组患者肌钙蛋白和BNP水平的监测结果,以及患者的住院天数。结果:观察组在入院时和术后7天的肌钙蛋白水平均低于对照组,分别为(0.065±0.023)ng/mL和(0.032±0.011)ng/mL,而对照组为(0.098±0.035)ng/mL和(0.076±0.027)ng/mL。通过t检验可知,两组之间的肌钙蛋白水平差异显著(P<0.05)。同样,观察组在入院时和术后7天的BNP水平也均低于对照组,分别为(115.678±30.567)pg/mL和(85.321±20.123)pg/mL,而对照组为(168.901±40.234)pg/mL和(130.456±30.789)pg/mL。两组之间的BNP水平也差异显著(P<0.05)。结论:肌钙蛋白和BNP水平在脑动脉瘤破裂出血患者预后的预测中具有一定的价值。肌钙蛋白和BNP水平的升高可能预示着不良预后,因此其监测可以作为一种预测脑动脉瘤破裂出血预后风险的辅助工具。Objective:This study aims to analyze the role of troponin and BNP monitoring in predicting the prognosis of cerebral aneurysm rupture and hemorrhage in neurosurgery.Method:A retrospective analysis was conducted on clinical data of patients with cerebral aneurysm rupture and hemorrhage from 2017 to September 2023,and the patients were divided into observation group(good prognosis)and control group(poor prognosis)according to the prognosis.The monitoring results of troponin and BNP levels,as well as the length of hospital stay were compared between the two groups.Result:The levels of troponin in the observation group were lower than those in the control group at admission and 7 days after surgery,with values of(0.065±0.023)ng/mL and(0.032±0.011)ng/mL,respectively,while the control group had values of(0.098±0.035)ng/mL and(0.076±0.027)ng/mL.Through t-test,there was a statistically significant difference in the levels of troponin between the two groups(P<0.05).Similarly,the BNP levels in the observation group were lower than those in the control group at admission and 7 days after surgery,with values of(115.678±30.567)pg/mL and(85.321±20.123)pg/mL,respectively,while the control group had values of(168.901±40.234)pg/mL and(130.456±30.789)pg/mL.There were also statistical differences in BNP levels between the two groups(P<0.05).Conclusion:Troponin and BNP levels have a certain value in predicting the prognosis of patients with cerebral aneurysm rupture and hemorrhage.Elevated levels of troponin and BNP may indicate poor prognosis,so their monitoring can serve as an auxiliary tool for predicting the risk of cerebral aneurysm rupture and hemorrhage.

关 键 词：神经外科领域 肌钙蛋白 脑利钠肽监测 

分 类 号：R743[医药卫生—神经病学与精神病学]