高效液相色谱法分析丁二酸中7种有机酸的含量  

Analysis of Seven Organic Acids in Succinic Acid by High-performance Liquid Chromatography

作　　者：原晓丽 孙新营 司江坤 赵家宝 魏道欣 何莉 YUAN Xiaoli;SI Jiangkun;WEI Daoxin;HE Li(Xinjiang Zhizhen Chemical Engineering Research Center Co.,Ltd.,Shihezi 832000,China)

机构地区：[1]新疆至臻化工工程研究中心有限公司,新疆石河子832000 [2]新疆天业股份有限公司,新疆石河子832000

出　　处：《化工技术与开发》2024年第12期65-69,共5页Technology & Development of Chemical Industry

基　　金：第八师石河子市科技计划项目(2022JB02)。

摘　　要：丁二酸中的杂质有机酸,会直接影响生物可降解聚酯的聚合效果及产品的结构和性能。在马来酸水相加氢生产丁二酸的过程中,存在乙酸、丙烯酸、丙酸等单酸杂质以及马来酸、富马酸、苹果酸等不饱和脂肪酸杂质。本文建立了可同时测定丁二酸等7种有机酸含量的高效液相色谱法,并确定了分析条件。结果表明,所建立的丁二酸等7种有机酸的标准曲线呈良好的线性关系,相关系数为0.99995~0.99999,方法的加标回收率在95%~110%之间,相对偏差RSD在0.125%以下。The impurity organic acid in succinic acid directly affected the polymerization of biodegradable polyester,the structure and properties of the product.Monoacid impurities such as acetic acid,acrylic acid and propionic acid,as well as unsaturated fatty maleic acid,fumaric acid and malic acid,were present in the process of succinic acid production by aqueous hydrogenation of maleic acid.In this paper,the high-performance liquid chromatography for simultaneous determination of seven organic acids,included succinic acid,were established,the analytical conditions were obtained.The results showed that the standard curves of succinic acid and the other seven organic acids showed a good linear relationship,and the correlation coefficients were 0.99995~0.99999.The recovery of this method was 95%~110%and the relative deviation RSD was less than 0.125%.

关 键 词：高效液相色谱法 丁二酸 有机酸 杂质 

分 类 号：O657.72[理学—分析化学]