儿童期创伤、依恋关系与精神分裂症的相关性分析  

Correlation analysis of childhood trauma,attachment relationships,and schizophrenia

作　　者：吴建桦 张淑茹 赵瑞珍 代娟 WU Jian-hua;ZHANG Shu-ru;ZHAO Rui-zhen;DAI Juan(Department of psychiatry,Meishan Mental Health Center,Meishan 620000,China)

机构地区：[1]眉山市中医医院(眉山市精神卫生中心)精神科,620000

出　　处：《临床精神医学杂志》2024年第6期469-472,共4页Journal of Clinical Psychiatry

摘　　要：目的:探讨儿童期创伤、依恋关系与精神分裂症的相关性。方法:选择2021年1月至2023年3月我院接诊的132例精神分裂症患者为病例组;另选取同期我院职工及职工家属132名作为对照组。问卷调查收集调查对象一般情况、中文版儿童期创伤问卷(childhood trauma questionnaire,CTQ)、中文版成人依恋量表(adult attachment scale,AAS)。比较2组调查对象CTQ、ASS,分析不同临床特征精神分裂症患者CTQ及ASS得分,并对精神分裂症患者CTQ、ASS进行相关性分析,并分析依恋关系对儿童期创伤与精神分裂的中介关系。结果:精神分裂组患者CTQ总表得分与ASS总表得分及两个量表各维度得分均高于对照组(P均<0.05)。精神分裂症患者阳性与阴性症状量表(positive and negative syndrome scale,PANSS)得分与CTA、ASS总表及各分量表得分均呈正相关关系,CTA、ASS总表及各分量表得分间均呈正相关关系(P均<0.05)。CTQ、ASS均对PANSS回归系数显著(β=0.309、0.277,P均<0.001);ASS在CTQ和PANSS起部分中介作用,其中介效应比占总效应的27.13%。结论:精神分裂症患者儿童期创伤、依恋回避及依恋焦虑均高于正常人群,依恋关系在儿童期创伤和精神分裂症间起部分中介作用。Objective:To explore the correlation between childhood trauma,attachment relationships,and schizophrenia.Method:From January 2021 to March 2023,132 patients with schizophrenia admitted to our hospital were chosen as the case group,while another 132 employees and family members of employees from our hospital during the same period were chosen as the control group.A questionnaire survey was conducted to collect the general information of the survey subjects,the childhood trauma questionnaire(CTQ),and the adult attachment scale(AAS).The CTQ and ASS scores of two groups of survey subjects were compared,the CTQ and ASS scores of schizophrenia patients with different clinical characteristics were analyzed,and correlation analysis on the CTQ and ASS of schizophrenia patients were conducted,and the mediating relationship between attachment relationship and childhood trauma and schizophrenia were analyzed.Results:The total scores of CTQ and ASS scales,as well as the scores of each dimension of the two scales,were higher in the schizophrenia group than in the control group(all P<0.05).The positive and negative syndrome scale(PANSS)score of patients with schizophrenia is positively correlated with the scores of the CTA,ASS total table,and various subscales,while the scores of the CTA,ASS total table,and various subscales are positively correlated(all P<0.05).CTQ、ASS has a significant impact on PANSS regression coefficient(β=0.309、0.277,all P<0.001);Therefore ASS plays a partial mediating role in CTQ and PANSS,with a mediating effect ratio accounting for 27.13%of the total effect.Conclusion:Schizophrenic patients have higher levels of childhood trauma,attachment avoidance,and attachment anxiety compared to the normal population,and attachment relationships play a partial mediating role between childhood trauma and schizophrenia.

关 键 词：儿童期创伤 依恋关系 精神分裂症 相关性 

分 类 号：R749.3[医药卫生—神经病学与精神病学]