空蝶鞍综合征的诊断、治疗研究进展  

Advances in diagnosis and treatment of empty sella syndrome

作　　者：黄鹏 朱星全 吴章红 李松 张银 HUANG Peng;ZHU Xingquan;WU Zhanghong;LI Song;ZHANG Yin(Department of Neurosurgery,People's Hospital of Shapingba District,Chongqing 400032,China)

机构地区：[1]重庆市沙坪坝区人民医院神经外科,重庆400032 [2]陆军军医大学第二附属医院神经外科

出　　处：《临床神经外科杂志》2024年第6期698-701,共4页Journal of Clinical Neurosurgery

基　　金：重庆市自然科学基金面上项目(cstc2019jcyj-msxmX0475)。

摘　　要：空蝶鞍综合征(ESS)的特征表现为蛛网膜下腔疝入蝶鞍,致使垂体不同程度扁平,进而引起一系列的症状。目前原发性空蝶鞍(PESS)的发病机制尚不明确,存在鞍膈发育不全、颅内压升高、垂体体积变化等假说;继发性空蝶鞍综合征(SESS)多由鞍区手术、感染、放化疗等导致。大多数ESS患者表现为无症状,但仍有部分患者表现出顽固且无法忍受的头痛、严重的视力视野损害、内科无法纠正的激素失调等症状。对于空蝶鞍综合征患者的视觉障碍,明确手术指征并优化手术方式以最大程度改善视觉损害是亟待解决的问题。Empty sella syndrome(ESS)is characterized by herniation of the subarachnoid space into the sella,resulting in varying extent of flattening of the pituitary gland,which in turn causes a series of symptoms.At present,the pathogenesis of primary empty sella syndrome(PESS)is not very clear,but there are hypotheses such as underdevelopment of the sellar diaphragm,increased intracranial pressure and changes in pituitary gland volume.Secondary empty sella syndrome(SESS)is mostly caused by sellar area surgery,infection,radiotherapy and chemotherapy.Although most patients with ESS are asymptomatic,some patients still present with symptoms such as stubborn and intolerable headaches,severe visual field damage and hormonal imbalance that cannot be corrected by medical medicine.For patients with ESS who have visual impairment,it is urgent to clarify the surgical indications and optimize the surgical method to alleviate the symptons.

关 键 词：空蝶鞍综合征 原发性空蝶鞍综合征 继发性空蝶鞍综合征 垂体功能低下 视觉障碍 

分 类 号：R651[医药卫生—外科学]