血栓弹力图联合凝血功能检测在脑梗死患者治疗中的指导作用研究  

Study on the Guiding Effect of Thromboelastography Combined with Coagulation Function Testing in Treatment of Cerebral Infarction Patients

作　　者：蒋章进 王晓刚 JIANG Zhangjin;WANG Xiaogang(Blood Transfusion Department,Guangxi Zhuang Autonomous Region Guidong People's Hospital,Wuzhou,Guangxi 543001)

机构地区：[1]广西壮族自治区桂东人民医院输血科,广西梧州543001

出　　处：《智慧健康》2024年第29期53-56,共4页Smart Healthcare

摘　　要：目的探究血栓弹力图联合凝血功能检测在脑梗死患者治疗中的指导作用。方法选取2023年1—10月在广西壮族自治区桂东人民医院接受治疗的50例脑梗死患者作为研究组,并选取同期于该院进行健康体检的50例体检者作为对照组。通过血栓弹力图和常规凝血试验指标对两组的凝血功能进行评估,并对所得检验结果进行对比分析。结果研究组的凝血酶形成时间、凝血反应时间明显低于对照组(P<0.05);研究组α角、血栓最大振幅、凝血综合指数明显高于对照组(P<0.05)。研究组中的凝血酶原时间、活化部分凝血酶原时间、凝血酶时间明显低于对照组(P<0.05);研究组中的纤维蛋白原明显高于对照组(P<0.05);研究组与对照组的血小板计数无明显差异(P>0.05)。结论血栓弹力图联合凝血功能检测在脑梗死患者治疗中具有重要的指导作用,通过联合检测可以更准确地评估患者的凝血功能状态,制定出更具针对性的治疗方案,值得推广。Objective To explore the guiding effect of thromboelastography combined with coagulation function testing in treatment of patients with cerebral infarction.Methods The paper chose 50 patients with cerebral infarction in Guidong People's Hospital of Guangxi as the study group,and 50 healthy examinees in the hospital for physical examination during the same period as the control group randomly,with case collection period from January 2023 to October 2023.Coagulation function was evaluated with thromboelastography and routine coagulation test indicators,and test results were compared between two groups.Results Thrombin formation time and coagulation reaction time in the study group was significantly lower than the control group,P<0.05.Theαangle,maximum thrombus amplitude and coagulation composite index of the study group were significantly higher than the control group,P<0.05.The prothrombin time,activated partial thromboplastin time,and coagulation enzyme time of the study group was significantly lower than the control group,P<0.05.Fibrinogen in the study group was significantly higher than the control group,P<0.05.There was no significant difference in platelet counts between the study group and the control group,P>0.05.Conclusion Thromboelastography combined with coagulation function testing can achieve important guiding effect in treatment of cerebral infarction patients.Coagulation function status of patients can be accurately evaluated by combined detection,and more targeted treatment plans can be formulated,which is worthy of promotion.

关 键 词：血栓弹力图 凝血功能检测 脑梗死 

分 类 号：R743.33[医药卫生—神经病学与精神病学]