含氮环烷烃选择性构建功能化芳烃研究进展  

Progress in Selective Construction of Functional Aromatics from Nitrogenous Cycloalkanes

作　　者：张云皓 王一诺 王思然 徐大振[1] Yunhao Zhang;Yinuo Wang;Siran Wang;Dazhen Xu(Department of Chemistry,Nankai University,Tianjin 300071,China.)

机构地区：[1]南开大学化学学院,农药国家工程研究中心,天津300071

出　　处：《大学化学》2024年第11期136-145,共10页University Chemistry

基　　金：国家级大学生创新创业训练计划(202210055082,202310055078)。

摘　　要：含氮杂环类化合物广泛存在于自然界,具有多种生物活性。近几年,使用含氮环烷烃作为原料合成含氮芳烃成为目前的一个研究热点,该方法无需导向基团,可选择性地一步实现C―C、C―N、C―S和C―Se键的构建和芳构化。本文整理了近年来有关该方法构建功能化喹啉和吲哚的文献报道,进行了系统的梳理和综述,并对该领域未来的发展作出展望。Nitrogen-containing aromatic compounds are ubiquitous in nature.They often exhibit a wide range of biological activities.Therefore,chemists have been studying on the preparation of them for a long time as well as developing various methods for their derivatization.Recently,the direct oxidation of nonaromatic cyclicsubstrates to prepare selectively substituted aromatics has been one of research focuses.In which,the functionalized aromatics could be obtained via C―C,C―N,C―S and C―Se bonds formation without the directing groups in one step.This paper reviews the recent progress in the construction of functional quinoline and indole by this method,and proposes future development prospects in this field.

关 键 词：吲哚 喹啉 去氢化 芳构化 

分 类 号：G64[文化科学—高等教育学] O6[文化科学—教育学]