电化学氧化硫醚制备亚砜  

Electrochemical Oxidation of Sulfides to Sulfoxides

作　　者：张林宝 郭维斯[1] 王书文[1] 宋然 李明[1] Linbao Zhang;Weisi Guo;Shuwen Wang;Ran Song;Ming Li(College of Chemistry and Molecular Engineering,Qingdao University of Science and Technology,Qingdao 266042,Shandong Province,China.)

机构地区：[1]青岛科技大学化学与分子工程学院,山东青岛266042

出　　处：《大学化学》2024年第11期204-209,共6页University Chemistry

基　　金：青岛科技大学一流本科课程建设项目(2021020);山东省一流本科课程建设项目(2021309)。

摘　　要：电化学合成是一种绿色、高效、可持续的有机合成方案,但在本科基础实验中的应用并未有效推广。亚砜类化合物常见于功能性有机化合物中,在天然的药物或材料中也有广泛应用。对于亚砜类化合物合成方法的研究在有机合成领域一直是热点话题,但传统的方法存在诸多缺陷。我们开发了一种以氯化钠为电解质将硫化物选择性氧化为亚砜的电化学方案,其中氯化钠起双重作用:(1)作为电解质;(2)作为氧化还原介质。Electrochemical synthesis is a green,efficient,and sustainable organic synthesis scheme,but its application in undergraduate basic experiments has not been effectively promoted.Sulfoxide compounds are commonly found in functional organic compounds and are also widely used in natural drugs or materials.The research on the synthesis methods of sulfoxide compounds has always been a hot topic in the field of organic synthesis,but traditional methods have many shortcomings.We have developed an electrochemical scheme for selectively oxidizing sulfides to sulfoxides,where sodium chloride plays a dual role:(1) as an electrolyte;(2) as a redox mediator.

关 键 词：电化学 硫醚 亚砜 

分 类 号：G64[文化科学—高等教育学] O6[文化科学—教育学]