半程数字化导板口腔种植修复联合口腔洁含漱液对慢性牙周炎患者龈沟液AST、OPN水平的影响  

Effect of Semi-digital Guide Plate Oral Implant Restoration Combined with Oral Cleansing Rinse on Gingival Sulcus Fluid AST and OPN Levels in Patients with Chronic Periodontitis

作　　者：杨丹 雷明辉 崔立丰 文雨 付敬敏 YANG Dan;LEI Ming-hui;CUI Li-feng;WEN Yu;FU Jing-min(Department of Stomatology,The Affiliated Hospital of Shaanxi University of Chinese Medicine,Xianyang,Shaanxi,712000,China;Department of Stomatology,The First People's Hospital of Xianyang,Xianyang,Shaanxi,712000,China)

机构地区：[1]陕西中医药大学附属医院口腔科,陕西咸阳712000 [2]咸阳市第一人民医院口腔科,陕西咸阳712000

出　　处：《现代生物医学进展》2024年第23期4526-4528,共3页Progress in Modern Biomedicine

基　　金：陕西省科技厅重点研发项目(2023-YBSF-300)。

摘　　要：目的:探究半程数字化导板口腔种植修复联合口腔洁含漱液对慢性牙周炎患者龈沟液天门冬氨酸氨基转氨酶(AST)、骨桥蛋白(OPN)水平的影响。方法:研究对象为2021.1-2024.4于我院治疗的90例慢性牙周炎患者,通过随机数字表法分组,对照组(半程数字化导板口腔种植修复)43例,观察组(半程数字化导板口腔种植修复+金栀洁龈含漱液)47例,治疗1个月,比较两组的各项指标。结果:与对照组比,观察组治疗总有效率更高(P<0.05);治疗后1个月观察组牙周指标水平、AST、OPN、ALP水平均低于对照组(P<0.05);观察组生活质量各维度评分及并发症总发生率均低于对照组(P<0.05)。结论:半程数字化导板口腔种植修复联合口腔洁含漱液治疗慢性牙周炎临床疗效显著,可有效改善牙周状态指标,降低AST、OPN、ALP水平,提高患者生活质量,且并发症发生率较低。Objective:To investigate the effect of semi-digital guided oral implant restoration combined with oral cleansing rinse on gingival sulcus fluid aspartate amino transferase(AST)and Osteopontin(OPN)levels in patients with chronic periodontitis.Methods:The research subjects were 90 patients with chronic periodontitis treated in our hospital from January 2021 to April 2024.They were randomly divided into two groups using a random number table method:a control group of 43 cases(half stage digital guide plate oral implant restoration)and an observation group of 47 cases(half stage digital guide plate oral implant restoration+Jinzhijie gingival mouthwash).After one month of treatment,the various indicators of the two groups were compared.Results:Compared with the control group,the observation group had a higher total effective rate of treatment(P<0.05);After one month of treatment,the periodontal index levels,AST,OPN,and ALP levels in the observation group were lower than those in the control group(P<0.05);The scores of various dimensions of quality of life and the total incidence of complications in the observation group were lower than those in the control group(P<0.05).Conclusion:The clinical efficacy of semi-process digital guide plate oral implant restoration combined with oral cleansing rinse in the treatment of chronic periodontitis is remarkable,which can effectively improve the periodontal status indexes,reduce the level of AST,OPN,ALP,and improve the quality of life of the patients,and the complication rate is low.

关 键 词：慢性牙周炎 口腔种植修复 数字化导板 

分 类 号：R781.4[医药卫生—口腔医学]