柴芍解郁丸联合眼周穴位针刺治疗肝郁气滞型高眼压症临床研究  

Clinical Study on Chaishao Jieyu Pills Combined with Acupuncture at Periocular Acupoints for Ocular Hypertension of Liver Constraint and Qi Stagnation Type

作　　者：巨磊 武丹 李娜 JU Lei;WU Dan;LI Na(Department of Ophthalmology,Chinese Medicine Hospital of Puyang,Puyang Henan 457001,China;Rehabilitation Department,Chinese Medicine Hospital of Puyang,Puyang Henan 457001,China;Function Department,Chinese Medicine Hospital of Puyang,Puyang Henan 457001,China)

机构地区：[1]濮阳市中医医院眼科,河南濮阳457001 [2]濮阳市中医医院康复科,河南濮阳457001 [3]濮阳市中医医院功能科,河南濮阳457001

出　　处：《新中医》2024年第24期94-98,共5页New Chinese Medicine

摘　　要：目的:观察柴芍解郁丸联合眼周穴位针刺治疗肝郁气滞型高眼压症(OHT)的临床效果。方法:选择肝郁气滞型OHT患者100例,按随机数字表法分为2组各50例。对照组给予眼周穴位针刺治疗,观察组在对照组基础上联合柴芍解郁丸治疗。比较2组中医证候评分、眼压和最佳矫正视力、血流动力学指标[眼动脉阻力指数(RI)、舒张末期血流速(EDV)、收缩期血流速峰值(PSV)]、临床疗效和复发率。结果:观察组总有效率为98.00%,对照组为84.00%,2组比较,差异有统计学意义(P<0.05)。治疗后,2组眩晕、目珠痛、头痛、烦躁易怒、胸胁胀满等中医证候评分均较治疗前降低(P<0.05),且观察组各项评分均低于对照组(P<0.05)。治疗后,2组眼压较治疗前下降(P<0.05),最佳矫正视力较治疗前升高(P<0.05);且观察组眼压低于对照组(P<0.05),最佳矫正视力高于对照组(P<0.05)。治疗后,2组眼动脉RI值较治疗前降低(P<0.05),EDV、PSV水平较治疗前升高(P<0.05);且观察组RI值低于对照组(P<0.05),EDV、PSV水平高于对照组(P<0.05)。随访2个月,观察组复发率为8.16%,对照组为26.19%,2组比较,差异有统计学意义(P<0.05)。结论:柴芍解郁丸联合眼周穴位针刺能够明显改善患者中医证候及眼部血流,降低眼压,提高最佳矫正视力,减少复发。Objective:To observe the clinical effect of Chaishao Jieyu Pills combined with acupuncture at periocular acupoints on ocular hypertension(OHT)of liver constraint and qi stagnation type.Methods:A total of 100 cases of patients with OHT of liver constraint and qi stagnation type were selected and divided into two groups according to the random number table method,with 50 cases in each group.The control group was treated with acupuncture at periocular acupoints,and the observation group was treated with Chaishao Jieyu Pills in addition to the control group's treatment.The two groups were compared in terms of traditional Chinese medicine(TCM)syndrome scores,intraocular pressure,best corrected visual acuity,hemodynamic indicators[ocular artery resistance index(RI),end-diastolic blood flow velocity(EDV),peak systolic blood flow velocity(PSV)],clinical effects,and recurrence rates.Results:The total effective rate was 98.00%in the observation group and 84.00%in the control group,the difference being significant(P<0.05).After treatment,the scores of dizziness,eyeball pain,headache,vexation,agitation and irascibility,and fullness in chest and hypochondrium in the two groups were decreased when compared with those before treatment(P<0.05),and the scores in the observation group were lower than those in the control group(P<0.05).After treatment,the intraocular pressure in the two groups was reduced when compared with that before treatment(P<0.05),and the best corrected visual acuity was increased(P<0.05);the intraocular pressure in the observation group was lower than that in the control group(P<0.05),and the best corrected visual acuity was higher than that in the control group(P<0.05).After treatment,the ocular artery RI in the two groups were decreased(P<0.05),and the EDV and PSV were increased(P<0.05);the RI in the observation group was lower than that in the control group(P<0.05),and the EDV and PSV were higher than those in the control group(P<0.05).After a two-month follow-up,the recurrence rate was 8.16%in the observ

关 键 词：高眼压症 肝郁气滞型 柴芍解郁丸 针刺疗法 血流动力学 

分 类 号：R775[医药卫生—眼科]