美容缝合技术联合外用重组人碱性成纤维细胞生长因子修复面部外伤的疗效观察  

Efficacy of cosmetic suturing techniques combined with topical recombinant human basic fibroblast growth factor in repairing facial trauma

作　　者：练慧斌[1] 李平松[1] 荣坤杰 徐刚[1] 周杰[1] 罗艺[1] 主父中印 鞠海宾 金俊俊 焦瑞 张筱薇 殷志敏 Lian Huibin;Li Pingsong;Rong Kunjie;Xu Gang;Zhou Jie;Luo Yi;Zhufu Zhongyin;Ju Haibin;Jin Junjun;Jiao Rui;Zhang Xiaowei;Yin Zhimin(Department of Burns and Plastic Surgery,North Jiangsu People's Hospital,Yangzhou 225001,China)

机构地区：[1]苏北人民医院烧伤整形科,扬州225001

出　　处：《中华医学美学美容杂志》2024年第6期571-575,共5页Chinese Journal of Medical Aesthetics and Cosmetology

基　　金：江苏省中医药科技发展计划项目(YB2020086);扬州市政策引导计划(YZ2022237)。

摘　　要：目的观察美容缝合技术联合外用重组人碱性成纤维细胞生长因子(rh-bFGF)修复面部外伤的疗效。方法前瞻性纳入2022年1至12月苏北人民医院烧伤整形科140例面部外伤患者,根据不同的治疗方法,采用随机数字表法将患者分为2组。治疗组70例,其中男38例,女32例,年龄3~54(23.1±8.2)岁,采用美容缝合技术联合外用rh-bFGF修复伤口。对照组70例,其中男36例,女34例,年龄2~49(22.3±7.5)岁,仅采用美容缝合技术修复伤口。术后2周对患者进行随访,评价切口愈合质量。采用视觉模拟评分法(VAS)进行患者满意度评估。术后6个月,采用温哥华瘢痕评分量表(VSS)对瘢痕情况进行评估。结果治疗组直接缝合65例,采用皮瓣修复5例,甲级愈合率为100%(70/70);对照组患者直接缝合66例,采用皮瓣修复4例,甲级愈合率为91.4%(64/70);治疗组甲级愈合率高于对照组,差异有统计学意义(P=0.037)。术后2周,治疗组患者手术满意度VAS评分为(1.13±0.52)分,低于对照组的(2.56±1.32)分,差异有统计学意义(P<0.001)。术后6个月,治疗组患者VSS评分为(2.49±1.27)分,低于对照组的(4.67±1.93)分,差异有统计学意义(P<0.001)。结论美容缝合技术联合外用rh-bFGF修复面部外伤能够提高伤口愈合质量,减轻伤口瘢痕,提高患者手术满意度。ObjectiveTo observe the efficacy of cosmetic suturing techniques combined with topical recombinant human basic fibroblast growth factor(rh-bFGF)in repairing facial trauma.MethodsA prospective study was conducted on 140 patients with facial trauma admitted to the Department of Burn and Plastic Surgery,Northern Jiangsu People's Hospital from January to December 2022.Patients were divided into two groups based on different treatment methods using a random number table method:treatment group(70 cases),including 38 males and 32 females aged 3 to 54(23.1±8.2)years,received cosmetic suturing techniques combined with topical rh-bFGF for wound repair;control group(70 cases),including 36 males and 34 females aged 2 to 49(22.3±7.5)years,only received cosmetic suturing techniques for wound repair.Patients were followed up 2 weeks post-surgery to evaluate wound healing quality.Patient satisfaction was assessed using the visual analogue scale(VAS).Six months post-surgery,scar conditions were evaluated using the Vancouver scar scale(VSS).ResultsIn the treatment group,65 cases were directly sutured,and 5 cases were repaired with skin flaps,with a first-class healing rate of 100%(70/70).In the control group,66 cases were directly sutured,and 4 cases were repaired with skin flaps,with a first-class healing rate of 91.4%(64/70).The first-class healing rate in the treatment group was higher than that in the control group,with a statistically significant difference(P=0.037).Two weeks post-surgery,the VAS score for surgical satisfaction in the treatment group was(1.13±0.52)scores,which was lower than that in the control group(2.56±1.32)scores,with a statistically significant difference(P<0.001).Six months post-surgery,the VSS score for the treatment group was(2.49±1.27)scores,which was lower than that in the control group(4.67±1.93)scores,with a statistically significant difference(P<0.001).ConclusionsIn repairing facial trauma,the combination of cosmetic suturing techniques and topical rh-bFGF can improve wound healing quality,

关 键 词：外伤 美容缝合技术 外用重组人碱性成纤维细胞生长因子 心形缝合 瘢痕 

分 类 号：R782.2[医药卫生—口腔医学]