精神分裂症神经认知评估工具的指引推荐及临床实践应用问题分析  

Guidance recommendation and clinical practice issues in neurocognitive assessment tools for schizophrenia

作　　者：刘登堂[1] 陆峥[2] 于欣[3] 邓红[4] 石川[3] 刘莎[5] 刘哲宁[6] 张天宏[1] 李晓白[7] 蒲城城[3] Liu Dengtang;Lu Zheng;Yu Xin;Deng Hong;Shi Chuan;Liu Sha;Liu Zhening;Zhang Tianhong;Li Xiaobai;Pu Chengcheng(Shanghai Mental Health Center,Shanghai Jiao Tong University School of Medicine,Shanghai200030,China;Mental Health Center,Tongji Hospital of Tongji University,Shanghai200065,China;Peking University Sixth Hospital,Peking University Institute of Mental Health,NHC Key Laboratory of Mental Health(Peking University),National Clinical Research Center for Mental Disorders(Peking University Sixth Hospital),Beijing100191,China;Mental Health Center,West China Hospital of Sichuan University,Chengdu610041,China;Department of Psychiatry,First Hospital of Shanxi Medical University,Shanxi Key Laboratory of Artificial Intelligence Assisted Diagnosis and Treatment for Mental Disorder,Taiyuan030001,China;Department of Psychiatry,the Second Xiangya Hospital of Central South University,National Clinical Research Center for Mental Disorders,National Center for Mental Disorders,Changsha410011,China;Department of Psychiatry,the First Affiliated Hospital of China Medical University,Shenyang110001,China)

机构地区：[1]上海交通大学医学院附属精神卫生中心,上海200030 [2]同济大学附属同济医院精神医学中心,上海200065 [3]北京大学第六医院、北京大学精神卫生研究所、国家卫生健康委员会精神卫生学重点实验室(北京大学)国家精神心理疾病临床医学研究中心(北京大学第六医院),北京100191 [4]四川大学华西医院心理卫生中心,成都610041 [5]山西医科大学第一医院精神卫生科、精神障碍人工智能辅助诊疗山西省重点实验室,太原030001 [6]中南大学湘雅二医院精神病学科、国家精神心理疾病临床研究中心、国家精神疾病医学中心,长沙410011 [7]中国医科大学附属第一医院精神科,沈阳110001

出　　处：《中华精神科杂志》2024年第12期789-795,共7页Chinese Journal of Psychiatry

基　　金：上海市精神卫生中心临床研究中心重点项目(CRC2017ZD03);国家自然科学基金(82371504, 82171496);上海市卫生健康委员会新兴交叉领域研究专项(2022JC009)。

摘　　要：尽管认知损害被认为是精神分裂症的核心症状, 并对功能结局有重要影响, 但在临床实践中却易被忽视。2022年, 欧洲精神病学协会发布了《精神分裂症认知功能损害评估指引》, 为研究与临床实践提供建议。本文将解读指引中涉及的精神分裂症的神经认知内容, 介绍中国神经认知的评估工具及应用场景、认知损害主观与客观评定的关系, 简述神经认知与阳性症状、阴性症状关系, 并展望中国神经认知评估工具的未来发展。Although cognitive impairment is considered a core symptom of schizophrenia and significantly impacts functional outcomes,it is often overlooked in clinical practice.The European Psychiatric Association released“Guideline on Assessment of Cognitive Impairment in Schizophrenia”in 2022,providing recommendations for research and clinical practice.This paper interprets the neurocognitive aspects of schizophrenia covered in the guidelines,introduces neurocognitive assessment tools used in China and their application settings,examines the relationship between subjective and objective assessments of cognitive impairment,and briefly discusses the connections between neurocognition and positive and negative symptoms.The paper also considers the future development of neurocognitive assessment tools in China.

关 键 词：精神分裂症 神经认知 评估工具 指南解读 

分 类 号：R749.3[医药卫生—神经病学与精神病学]