Characterization of chitosan/α-lactalbumin nanocomplex particle and its encapsulation for retinol  

作　　者：Zhanmei Jiang Jinzhe Li Wei Chen Muhammad Altaf Hussain Xuan Wei Akhunzada Bilawal Juncai Hou 

机构地区：[1]Key Laboratory of Dairy Science(Northeast Agricultural University),Ministry of Education,College of Food Science,Northeast Agricultural University,Harbin,150030,PR China [2]Lasbela University of Agriculture,Water and Marine Science,Uthal,90150,Balochistan,Pakistan

出　　处：《Food Bioscience》2023年第1期397-404,共8页食品生物科学（英文）

基　　金：supported by project for the Natural Science Foundation of China(No.32172164);Natural Key Science Foundation of Heilongjiang Province of China(No.ZD2021C007);Key Program of Heilongjiang Province of China(No.2019ZX07B02-04).

摘　　要：Chitosan(Ct)andα-lactalbumin(ALa)were applied as the carriers,their biopolymer nanoparticle was designed to encapsulate retinol(VA).Zeta potential and turbidity measurements,demonstrated that the most suitable pH value in the formation of Ct/ALa nanoparticle was 6.0,and its optimal Ct/ALa mass ratio was 1:4.At this ratio,scanning electron microscopy(SEM)of Ct/ALa nanoparticle showed that Ct was coated on the surface of ALa/VA as a shell.Meanwhile,the encapsulation efficiency(EE)and loading capacity(LC)of above nano-sized Ct/ALa particle for VA were 82.22±1.78%and 3.13±0.12%,respectively.Moreover,Ct/ALa nanoparticle not only improved the storage stability of VA,but also protected VA from the destruction of simulated gastrointestinal juice to a certain extent during in vitro digestion.Information from this study could supply the novel opinion for the protection and delivery of photosensitive bioactive substances(VA)in functional dairy-based product.

关 键 词：RETINOL Α-LACTALBUMIN CHITOSAN NANOPARTICLE Stability DIGESTION 

分 类 号：TB383[一般工业技术—材料科学与工程]