Α-LACTALBUMIN

作品数：14被引量：41H指数：3
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相关领域：轻工技术与工程生物学更多>>
相关作者：陈敏李慧戴蕴青李赫罗永康更多>>
相关机构：中国农业大学东北农业大学浙江省疾病预防控制中心武汉大学更多>>
相关期刊：《武汉大学学报（理学版）》《Asian Journal of Pharmaceutical Sciences》《色谱》《Science China(Life Sciences)》更多>>
相关基金：国家自然科学基金博士科研启动基金黑龙江省青年科学基金更多>>
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Unleashing the healing potential:Exploring next-generation regenerative protein nanoscaffolds for burn wound recovery
《Asian Journal of Pharmaceutical Sciences》2023年第6期100-112,共13页Liangwei Si Xiong Guo Hriday Bera Yang Chen Fangfang Xiu Peixin Liu Chunwei Zhao Yasir Faraz Abbasi Xing Tang Vito Foderà Dongmei Cun Mingshi Yang 
supported by the Liaoning Pan Deng Xue Zhe Scholar(No.XLYC2002061);the Overseas Expertise Introduction Project for Discipline Innovation(“111 Project”)(No.D20029);X.G.acknowledges the Educational Department of Liaoning Province(grant No.LJKZ0925),(Youth Project,grant No.LJKQZ2021035);the international postdoctoral exchange fellowship program(grant No.PC2021047);H.B.thanks the financial support from National Natural Science Foundation of China(grant No.82050410448);Fellowship of China Postdoctoral Science Foundation(grant No.2021MD703857);D.Cun acknowledges financial support from Ministry of Education Chunhui Program(2020);VF acknowledges VILLUM FONDEN for supporting the project via the Villum Young Investigator Grant(grant No.19175).
Burn injury is a serious public health problem and scientists are continuously aiming to develop promising biomimetic dressings for effective burn wound management.In this study,a greater efficacy in burn wound healin...
关键词：Regenerative proteins Α-LACTALBUMIN SEROTONIN Electrospinning Nanofibrous dressing Third-degree burn 
Au@Ag-labeled SERS lateral flow assay for highly sensitive detection of allergens in milk被引量：2
《Food Science and Human Wellness》2023年第3期912-919,共8页Jing Li Jia Xu Yi Pan Yongzhi Zhu Yuanfeng Wang Shouhui Chen Xinlin Wei 
supported by the Science and Technology Innovation Action Plan of Shanghai,China(17391901302);the National Key R&D Program of China(2018YFC1604401)。
Casein andα-lactalbumin(α-LA)are the main allergens in cow's milk,which can affect the skin,respiratory system,and gastrointestinal tract,even cause anaphylactic shock.Developing a rapid and sensitive detection meth...
关键词：CASEIN Α-LACTALBUMIN Au@AgNPs SERS-LFA 
Structure and allergenicity of a-lactalbumin:effects of ultrasonic prior to glycation and subsequent phosphorylation被引量：1
《Food Science and Human Wellness》2023年第3期825-831,共7页Wenmei Chen Qiongzhen Chen Houze Zhou Yanhong Shao Yang Wang Jun Liu Zongcai Tu 
supported by Science Foundation for Young Scientists of Jiangxi Province(20202BABL215027);National Natural Science Foundation of China(31960457)。
Bovineα-lactalbumin(BLA)induced severe cow's milk allergy.In this study,a novel strategy combining ultrasonication,performed before glycation,and phosphorylation was proposed to reduce BLA allergenicity.Result showed...
关键词：Bovineα-lactalbumin ALLERGENICITY ULTRASONIC Protein modification 
A new attempt to develop fermented milk with low whey protein allergenic potential using a top-down method
《Food Bioscience》2023年第3期1238-1248,共11页Ruiyang Ma Na Miao Qingyi Zhang Shujuan Jiang Xinling Li Lei Chi Yue Li Guangqing Mu Xuemei Zhu 
supported by Key Science and Technology program of Xinjiang Production and Construction Corps(2018AA009-02);Fund of Education Department of Liaoning Province(LJKZ0550).
The development process of fermented milk products with low-allergenic potential usually begins with the isolation and screening of strains.However,this bottom-up screening method is time-consuming and heavy workload....
关键词：Cows’milk protein allergy Α-LACTALBUMIN Β-LACTOGLOBULIN ANTIGENICITY ALLERGENICITY 
Characterization of chitosan/α-lactalbumin nanocomplex particle and its encapsulation for retinol被引量：1
《Food Bioscience》2023年第1期397-404,共8页Zhanmei Jiang Jinzhe Li Wei Chen Muhammad Altaf Hussain Xuan Wei Akhunzada Bilawal Juncai Hou 
supported by project for the Natural Science Foundation of China(No.32172164);Natural Key Science Foundation of Heilongjiang Province of China(No.ZD2021C007);Key Program of Heilongjiang Province of China(No.2019ZX07B02-04).
Chitosan(Ct)andα-lactalbumin(ALa)were applied as the carriers,their biopolymer nanoparticle was designed to encapsulate retinol(VA).Zeta potential and turbidity measurements,demonstrated that the most suitable pH val...
关键词：RETINOL Α-LACTALBUMIN CHITOSAN NANOPARTICLE Stability DIGESTION 
Simultaneous binding of folic acid and lutein to β-lactoglobulin and α-lactalbumin: A spectroscopic and molecular docking study
《Food Bioscience》2022年第6期973-981,共9页Danilo C.Vidotto Guilherme M.Tavares 
financed by the S˜ao Paulo Research Foundation(FAPESP)(Grants 2017/09214-4 and 2018/09304-6);The authors thank the Food Chemistry Laboratory(FEA/UNICAMP)for chromatographic analysis(FAPESP multiuser equipment:grants 2018/03822-5 and 2018/23752-1);Also,this research used facilities of the Brazilian Biorenewables National Laboratory(LNBR),part of CNPEM as well.The Macromolecules facility staff is acknowledged for the assistance during CD experiments(proposal MAC-28004).
Whey proteins are versatile molecules with great nutritional value and multiple functionalities. One of these functionalities is the ability to bind and protect bioactive compounds. Lutein and folic acid (FA) are bioa...
关键词：Whey proteins Multi-binding Folic acid LUTEIN Fluorescence quenching Molecular modeling 
Bioaccessibility and Cell Metabolic Activity Studies of Antioxidant Low Molecular Weight Peptides Obtained by Ultrafiltration of <i>α</i>-Lactalbumin Enzymatic Hydrolysates
《Food and Nutrition Sciences》2018年第9期1047-1065,共19页Adriana Maite Fernández-Fernández Eliane Dumay Tomás López-Pedemonte Alejandra Medrano-Fernandez 
α-lactalbumin (α-LA) might increase its antioxidant potential after hydrolysis. In particular, low molecular weight (LMW) peptides showed greater antioxidant capacity. Different hydrolysis conditions with Alcalase e...
关键词：Α-LACTALBUMIN Alcalase Hydrolysis ULTRAFILTRATION Bioactive Properties Gastrointestinal Digestion Simulation CELL Viability 
高效液相色谱法测定α-乳白蛋白和β-乳球蛋白被引量：8
《食品研究与开发》2013年第2期57-60,共4页王莹 屈玉霄 刘春红 冯志彪 
东北农业大学博士基金;黑龙江省青年基金(QC2010029)
采用HPLC法测定牛乳中主要过敏蛋白α-乳白蛋白及β-乳球蛋白的含量,其测定条件为:Agilent-C8(4.6 mm×150 mm,5μm)色谱柱,流动相A为含0.5%三氟乙酸的乙腈,流动相B为含0.1%三氟乙酸的超纯水,采用梯度洗脱的方法,流速1 mL/min,柱温25℃...
关键词：高效液相色谱(HPLC) α-乳白蛋白(α-lactalbumin) β-乳球蛋白(β-lactoglobulin) 
HPLC Analysis of α-lactalbumin and β-lactoglobulin in Bovine Milk with C_4 and C_(18) Column被引量：1
《Journal of Northeast Agricultural University(English Edition)》2012年第3期76-82,共7页Kong Xiao-yu Wang Jing Tang Yan-jun Li Dan-dan Zhang Nan-nan Jiang Jin-dou Liu Ning 
Supported by the Project of Science & Technology Plans in Heilongjiang Province in the 11th Five-year Period (GB07B407)
Reversed-phase high-performance liquid chromatography （RP-HPLC） method with C4 column and C18 column for analyzing β-lactoglobulin and α-lactalbumin in bovine milk was developed and the performance and characteris...
关键词：RP-HPLC bovine milk α-lactalbumin Β-LACTOGLOBULIN C4 column C18 column 
Effects of macromolecular crowding on the structural stability of human α-lactalbumin被引量：2
《Acta Biochimica et Biophysica Sinica》2012年第8期703-711,共9页De-Lin Zhang Ling-Jia Wu Jie Chen Yi Liang 
Acknowledgement The authors would like to thank Prof. Guang-Fu Yang （College of Chemistry, Central China Normal University） for his technical assistance on iTC200. Funding This work was supported by grants from the National Key Basic Research Foundation of China （2012CB911003）, the National Natural Science Foundation of China （30970599 and 31170744）, and the Fundamental Research Funds for the Central Universities of China （1104006）.
The folding of protein, an important process for protein to fulfill normal functions, takes place in crowded physiological environments, α-Lactalbumin, as a model system for proteinolding studies, has been used exten...
关键词：human α-lactalbumin macromolecularcrowding protein stability fluorescence spectroscopy circular dichroism trypsin digestion 
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