ANTIGENICITY

作品数：48被引量：164H指数：7
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相关作者：李晓明黄平更多>>
相关机构：空军军医大学（第四军医大学）广东省疾病预防控制中心武汉大学更多>>
相关期刊：《Grain & Oil Science and Technology》《Science China(Life Sciences)》《Frontiers in Biology》《Virologica Sinica》更多>>
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H3N2 influenza virus characteristics in China(2019-2022):Genetic,antigenic,and infection dynamics during the COVID-19 pandemic
《hLife》2025年第3期146-158,共13页Jiaming Li Yu Huan Qianfeng Xia Yan Li Rahat Ullah Khan Qingzhi Liu Chuanran Dou Marina Gulyaeva Alexander Shestopalov Ning Zhang Xuefeng Duan Jing Yang Hongchun Zhang Yuhai Bi 
supported by the National Key R&D Program of China(2022YFC3500804 and 2023YFC2307500 to Y.L.and Y.B.);the National Natural Science Foundation of China(NSFC)(32261133524 and 32425053 to Y.B.);the Beijing Research Center for Respiratory Infectious Diseases(BJRID2025-007 to Y.B.);the CAS Southeast Asia Biodiversity Research Institute(151C53KYSB20210023 to Y.B.);the Major Project of Guangzhou National Laboratory(GZNL2023A01001 to Y.B.);the National Science and Technology Infrastructure of China(National Pathogen Resource Center-NPRC-32 to Y.B.);the CAS Project for Young Scientists in Basic Research(YSBR-086 to Y.B.);the Youth Innovation Promotion Association of CAS(Y2021034 to Y.B.);the Innovation Team and Talents Cultivation Program of National Administration of Traditional Chinese Medicine(ZYYCXTD-D-202208 to Y.B.);the Russian Science Foundation(23-44-00026 to M.G.and A.S.).
Seasonal influenza activity significantly decreased in China during the coronavirus disease 2019(COVID-19)pandemic,yet the H3N2 virus led to three epidemic waves.Understanding the characteristics of H3N2 epidemic viru...
关键词：influenza Avirus H3N2 geneticevolution PHYLOGENY ANTIGENICITY infection 
Antigenic analysis of the influenza B virus hemagglutinin protein
《Virologica Sinica》2025年第1期80-91,共12页Mengyi Zhang Chaoying Yang Xi Wu Yifei Wang Lijie Wang Qianqian Cui Jincheng Tong Yimeng An Meina Cai Shishi Cheng Qi Jiang Yulin Wang Chenyan Zhao Youchun Wang Weijin Huang 
supported by a grant from the National Key R&D Program of China(No.2021YFC2301700);the Ministry of Science and Technology(China)of China(No.2021YFC2302500);the Establishment of a method for detecting neutralizing antibodies with pseudotyped viruses of China Pharmacopeia[grant number 2021S03].
Influenza B viruses(IBVs)primarily infect humans and are a common cause of respiratory infections in humans.Here,to systematically analyze the antigenicity of the IBVs Hemagglutinin(HA)protein,31 B/Victoria and 19 B/Y...
关键词：Influenza B virus(IBV) ANTIGENICITY Vaccine strains Pseudotyped viruses 
Antigenicity and genetic properties of an Eurasian avian-like H1N1 swine influenza virus in Jiangsu Province,China
《Biosafety and Health》2024年第6期319-326,共8页Fang He Huiyan Yu Liqi Liu Xiyan Li Yadong Xing Lei Yang Pengfei Yang Liguo Zhu Zi Li 
supported by the National Key Research and Development Program of China(Grant number 2023YFC2606500);Huai'an City Innovation Service Capacity Building Program(Key Laboratory Construction)(Grant number HAP201906);Jiangsu Province 333 Project.
Pigs are vital genetic mixing vessels for human and avian influenza viruses because their tracheal epitheliums possess both sialic acidα-2,6-Gal andα-2,3-Gal receptors.Cross-species transmission of influenza A virus...
关键词：Eurasian avian-like H1N1 swine influenza virus(EAH1N1 SIVs) Amino-acid sites ANTIGENICITY Drug resistance 
Genetic and biological properties of H9N2 avian influenza viruses isolated in central China from2020 to 2022
《Journal of Integrative Agriculture》2024年第8期2778-2791,共14页Libin Liang Yaning Bai Wenyan Huang Pengfei Ren Xing Li Dou Wang Yuhan Yang Zhen Gao Jiao Tang Xingchen Wu Shimin Gao Yanna Guo Mingming Hu Zhiwei Wang Zhongbing Wang Haili Ma Junping Li 
Fundamental Research Program of Shanxi Province,China(202103021224156);National Natural Science Foundation of China(32202788);Special Research Fund of Shanxi Agricultural University for High-level Talents,China(2021XG004);Science and Technology Innovation Program of Shanxi Agricultural University,China(2021BQ78);special fund for Science and Technology Innovation Teams of Shanxi Province,China(202304051001041);?Shanxi Province Excellent Doctoral Work Award-Scientific Research Project,China(SXBYKY2021005,SXBYKY2021063,SXBYKY2022014);the Fund for Shanxi“1331 Project”,China(20211331-13);earmarked fund for Modern Agro-industry Technology Research System of Shanxi Province,China.
The H9N2 subtype of avian influenza virus(AIV)is widely prevalent in poultry and wild birds globally,and has become the predominant subtype circulating in poultry in China.The H9N2 AIV can directly or indirectly(by se...
关键词：avian influenza virus H9N2 central China PATHOGENICITY ANTIGENICITY 
A new attempt to develop fermented milk with low whey protein allergenic potential using a top-down method
《Food Bioscience》2023年第3期1238-1248,共11页Ruiyang Ma Na Miao Qingyi Zhang Shujuan Jiang Xinling Li Lei Chi Yue Li Guangqing Mu Xuemei Zhu 
supported by Key Science and Technology program of Xinjiang Production and Construction Corps(2018AA009-02);Fund of Education Department of Liaoning Province(LJKZ0550).
The development process of fermented milk products with low-allergenic potential usually begins with the isolation and screening of strains.However,this bottom-up screening method is time-consuming and heavy workload....
关键词：Cows’milk protein allergy Α-LACTALBUMIN Β-LACTOGLOBULIN ANTIGENICITY ALLERGENICITY 
Characteristics of cold plasma treatment and enzymatic hydrolysis on IgG/IgE-binding ability of β-lactoglobulin被引量：1
《Food Bioscience》2022年第6期1696-1705,共10页Zhi-Wei Liu Lin-Lin Zhang Ying-Xue Zhou Pan-Pan Tang Yi-Cheng Tan Jun-Hu Cheng Amin Mousavi Khaneghah Rana Muhammad Aadil 
The foundation of the Leading Plan of High-tech and Innovation Industry Technology of Hunan Province(2022GK4014).
Characteristics of cold plasma (CP) treatment and enzymatic (papain and alcalase) hydrolysis on IgG/IgE-binding ability β-lactoglobulin (β-LG) were compared, which is analyzed by immunoblot, WB, ELISA, and LC-MS/MS ...
关键词：Β-LACTOGLOBULIN Cold plasma Enzyme hydrolysis ANTIGENICITY 
Genetic and biological characteristics of the globally circulating H5N8 avian influenza viruses and the protective efficacy offered by the poultry vaccine currently used in China被引量：23
《Science China(Life Sciences)》2022年第4期795-808,共14页Pengfei Cui Xianying Zeng Xuyong Li Yanbing Li Jianzhong Shi Conghui Zhao Zhiyuan Qu Yanwen Wang Jing Guo Wenli Gu Qi Ma Yuancheng Zhang Weipeng Lin Minghui Li Jingman Tian Dongxue Wang Xin Xing Yanjing Liu Shuxin Pan Yaping Zhang Hongmei Bao Liling Liu Guobin Tian Chengjun Li Guohua Deng Hualan Chen 
supported by the National Natural Science Foundation of China (31521005, 31672593);the Laboratory for Lingnan Modern Agriculture Project (NT2021007);the National Key Research and Development Program of China (2016YFD0500201);the China Agriculture Research System (CARS-41G12)
The H5N8 avian influenza viruses have been widely circulating in wild birds and are responsible for the loss of over 33 million domestic poultry in Europe, Russia, Middle East, and Asia since January 2020. To monitor ...
关键词：avian influenza virus H5N8 evolution PATHOGENICITY ANTIGENICITY VACCINE protective efficacy 
Human Seroreactivity to Secreted Molecules of Corynebacterium pseudotuberculosis
《Advances in Microbiology》2022年第3期150-158,共9页Ramon Mendes dos Santos Silvânia Maria Andrade Cerqueira Caio Lopez Borge Andrade Gabriel Saldanha Müller Vitória Costa de Menezes Santos Hévlyn Ribeiro de Araújo Samanta Queiroz Rogério Reis Conceição Luiz Gustavo Freitas Oliveira Marcos Borges Ribeiro Silvana Marchioro Lilia Ferreira de Moura-Costa Fúlvia Soares Campos de Sousa Maria da Conceição Aquino de Sá José Tadeu Raynal Rocha Filho Soraya Castro Trindade Eduardo Martins Netto Roberto Meyer Songelí Menezes Freire 
Corynebacterium pseudotuberculosis is an infectious agent that occurs in small ruminants causing caseous lymphadenitis, and more rarely in humans causing lymphadenitis and pneumonia. The breeding small ruminants have ...
关键词：Human Immunoreactivity ANTIGENICITY Corynebacterium pseudotuberculosis Secreted Proteins Western Blot 
Parallel profiling of antigenicity alteration and immune escape of SARS-CoV-2 Omicron and other variants被引量：3
《Signal Transduction and Targeted Therapy》2022年第3期770-779,共10页Cong Sun Yin-Feng Kang Yuan-Tao Liu Xiang-Wei Kong Hui-Qin Xu Dan Xiong Chu Xie Yi-Hao Liu Sui Peng Guo-Kai Feng Zheng Liu Mu-Sheng Zeng 
This work was supported by China’s National Key Research and Development Program(No.2016YFA0502100,No.2017YFA0505600);the National Natural Science Foundation of China(No.81801645,No.82030046).
SARS-CoV-2 variants have evolved a variety of critical mutations,leading to antigenicity changes and immune escape.The recent emerging SARS-CoV-2 Omicron variant attracted global attention due to its significant resis...
关键词：VARIANTS ANTIGENICITY OMI 
The antigenicity of SARS-CoV-2 Delta variants aggregated 10 high-frequency mutations in RBD has not changed sufficiently to replace the current vaccine strain被引量：1
《Signal Transduction and Targeted Therapy》2022年第2期492-501,共10页Jiajing Wu Jianhui Nie Li Zhang Hao Song Yimeng An Ziteng Liang Jing Yang Ruxia Ding Shuo Liu Qianqian Li Tao Li Zhimin Cui Mengyi Zhang Peng He Youchun Wang Xiaowang Qu Zhongyu Hu Qihui Wang Weijin Huang 
This work was supported by the General Program of the National Natural Science Foundation of China(grant number 82073621&82172244);National Key Research and Development Program of China(grant number 2021YFC0863300);Beijing Municipal Science and Technology Project(Z211100002521018);Bill&Melinda Gates Foundation(Investment ID INV-006379).
Emerging SARS-CoV-2 variants are the most serious problem for COVID-19 prophylaxis and treatment.To determine whether the SARS-CoV-2 vaccine strain should be updated following variant emergence like seasonal flu vacci...
关键词：vaccine ANTIGENICITY VARIANTS 
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