The effectiveness of polypeptides from phosvitin and eggshell membrane in enhancing the bioavailability of eggshell powder calcium and its accumulation in bones  

作　　者：Wei Liu Cuie Tang Zhaoxia Cai Yongguo Jin Dong Uk Ahn Xi Huang 

机构地区：[1]Key Laboratory of Environment Correlative Dietology,Ministry of Education,National Research and Development Center for Egg Processing,College of Food Science and Technology,Huazhong Agricultural University,Wuhan,Hubei,430070,PR China [2]Animal Science Department,Iowa State University,Ames,USA

出　　处：《Food Bioscience》2023年第1期531-540,共10页食品生物科学（英文）

基　　金：supported by the General Program of the National Natural Science Foundation of China(grant number 32072237);Hubei Provincial Natural Science Foundation(grant number 2020CFB583);Earmarked Fund for Modern Agro-industry Technology Research System(CARS-40-K24).

摘　　要：The low-calcium-specific pathogen-free C57BL/6(SPF-C57BL/6)mice were used to explore the effectiveness of phosvitin phosphopeptides(PPPs)and eggshell membrane peptides(EMPs)in improving the intestinal calcium absorption and promoting bone deposition of eggshell calcium(ESCa).Intake of ESCa+PPPs+EMPs significantly down regulated the abnormal elevation of serum alkaline phosphatase(ALP)induced by calcium deficiency.The CaCO3 group had lower calcium absorption rate(34.34%)and femur bone mineral density(BMD)(0.13 g/cm^(3)),while the ESCa+PPPs+EMPs treatment significantly improved calcium absorption rate(55.01%)and femur BMD(0.15 g/cm^(3)).The three-dimensional reconstruction images of mice femur showed that the ESCa+PPPs+EMPs group had a more complete,compact,and thicker trabecular structure than the low-calcium,CaCO3,and ESCa groups.These results indicated that the ESCa is a low-cost alternative calcium supplement to achieve adequate calcium intake,and the presence of polypeptides,such as PPPs and EMPs,is more beneficial to calcium absorption and deposition than the ESCa.

关 键 词：Eggshell powder Eggshell membrane Phosvitin phosphopeptide Calcium bioavailability Calcium deficient mice 

分 类 号：TS201.4[轻工技术与工程—食品科学]