注意缺陷多动障碍成人患者的跨期选择特征研究  

Characteristies of intertemporal choice in adults with attention deficit hyperactivity disorder

作　　者：洪海恒 陈彩丽 张诗雨 周怡 李海梅[1] 刘璐[1] 钱秋谨[1] 王玉凤[1] HONG Haiheng;CHEN Caili;ZHANG Shiyu;ZHOU Yi;Li Haimei;LlU Lu;QlAN Qiujin;WANG Yufeng(Peking University Sixth Hospital,Peking University Institute of Mental Health,NHc Key Laboratory of Mental Health(Peking Uni versity),National Clinical Research Center for Mental Disorders(Peking University Sixth Hospital),Beiing 100083,China)

机构地区：[1]北京大学第六医院,北京大学精神卫生研究所,国家卫生健康委员会精神卫生学重点实验室(北京大学),国家精神心理疾病临床医学研究中心(北京大学第六医院),北京100083

出　　处：《中国心理卫生杂志》2024年第12期1039-1044,共6页Chinese Mental Health Journal

摘　　要：目的:探索注意缺陷多动障碍(ADHD)成人患者跨期选择的延迟折扣特征及非系统响应数据特征,探索延迟折扣任务最佳数据处理策略。方法:纳入符合精神障碍诊断与统计手册第5版诊断标准的ADHD成人患者108例和性别匹配的正常对照87例,采用ADHD症状评定量表评估ADHD症状,使用延迟折扣任务测量延迟折扣率,使用无模型算法识别非系统响应数据。结果:ADHD组与正常对照组的非系统响应数据比例差异无统计学意义(P>0.05);在使用不同数据筛选策略的数据集中ADHD组延迟折扣率均高于正常对照组(均P<0.05);延迟折扣率与ADHD症状评定量表的多动冲动得分(r=0.24,P=0.001)、注意缺陷得分(r=0.20,P<0.01)及总得分(r=0.22,P<0.01)为正相关。结论:ADHD成人患者在跨期选择中偏好获得即时小奖励;跨期选择的即时偏好可能主要与多动冲动症状有关;排除非系统响应数据的数据处理策略可能更适用于延迟折扣任务研究。Objective:To explore the characteristics of delay discounting and non-systematic response data in intertemporal choice of adults with attention deficit hyperactivity disorder(ADHD),and to explore the best data processing strategy for delay discounting task.Methods:Totally 108 adults with ADHD meeting the diagnostic cri-teria of the Diagnostic and Statistical Manual of Mental Health Disorder,Fifth Edition(DSM-5)and 87 gender matched normal controls were enrolled.ADHD symptoms were assessed using the ADHD Symptom Rating Scale,the delay discounting task was used to measure the delay discounting rate,and a model-free algorithm was used to i-dentify non-systematic response data.Results:There was no significant difference in the proportion of non-systemat-ic response data between ADHD group and normal control group(P>0.05).In the data sets using different data screening strategies,the delay discounting rates were higher in the ADHD group than in the normal control group(Ps<0.05).The delay discounting rates were positively correlated with the hyperactive impulse scores(r=0.24,P=0.001),the inattention scores(r=0.20,P<0.01)and the total scores of ADHD symptom Rating Scale(r=0.22,P<0.01).Conclusion:Adults with ADHD prefer to obtain immediate small rewards in intertemporal choice.The immediate preference of intertemporal choice may be mainly related to hyperactive impulsive symp-toms.Exclusion strategy of non-systematic response data may be more applicable to delay discount task research.

关 键 词：跨期选择 注意缺陷多动障碍 延迟折扣任务 非系统响应数据 

分 类 号：R749.94[医药卫生—神经病学与精神病学]