胎儿颅内囊肿92例孕妇病例分析  

Analysis of 92 Pregnant Women with Fetal Intracranial Cyst

作　　者：马翠[1] 代天怡 杨晓月 山丹[1] MA Cui;DAI Tianyi;YANG Xiaoyue(Department of Obstetrics,Beijing Obstetrics and Gynecology Hospital,Capital Medical University,Beijing Maternal and Child Health Care Hospital,Beijing 100026,China)

机构地区：[1]首都医科大学附属北京妇产医院/北京妇幼保健院产科,北京100026

出　　处：《实用妇产科杂志》2024年第11期901-904,共4页Journal of Practical Obstetrics and Gynecology

基　　金：国家自然科学基金(编号:51673119)。

摘　　要：目的:比较分析胎儿颅内囊肿孕妇的妊娠结局相关影响因素以及遗传学结果,为颅内囊肿胎儿的产前咨询及临床治疗提供依据。方法:选取胎儿颅内囊肿的孕妇92例,通过电子病例系统收集其孕期及分娩相关资料,电话随访记录新生儿预后情况。根据妊娠结局分为继续妊娠组(80/92,87%)和引产组(12/92,13%),分析可能影响颅内囊肿胎儿妊娠结局的因素以及遗传学结果。结果:继续妊娠组和引产组比较,胎儿颅内囊肿诊断孕周≤28周和合并其他系统异常差异有统计学意义(P<0.05),而孕妇年龄、颅内囊肿数目差异无统计学意义(P>0.05)。共25例孕妇行遗传学检查,对遗传学检查结果正常和异常孕妇进行比较,孕妇年龄、诊断孕周、是否存在不良孕产史、是否为单发囊肿、胎儿是否合并其他系统异常差异均无统计学意义(P>0.05)。结论:胎儿颅内囊肿诊断孕周≤28周与合并其他系统异常是影响妊娠结局的危险因素。Objective:The pregnancy outcome,related influencing factors and genetic results of pregnant women with intracranial cysts were comparatively analyzed to provide evidence for prenatal consultation and clinical treatment of the fetus with intracranial cyst.Methods:A total of 92 pregnant women with fetal intracranial cysts were selected.The data of pregnancy and delivery were collected by electronic medical record system.The prognosis of newborn was recorded by telephone follow-up.According to the pregnancy outcome,they were divided into continued pregnancy group(80/92,87%)and induced labor group(12/92,13%).Analyze the factors that might influence the pregnancy outcome of intracranial cysts,as well as genetic outcomes.Results:Compared with the continued pregnancy group and the induced labor group,there were statistical differences between the gestation age at diagnosis≤28 weeks and the presence of other abnormalities(P<0.05),but there were no statistical differences in the age of pregnant women and the number of intracranial cysts(P>0.05).The results of genetic examination were compared between normal and abnormal groups of 25 cases,and there were no statistical differences in the age of pregnant women,the gestation age at diagnosis,whether there was adverse pregnancy history,whether there was single cyst,and the presence of other abnormalities(P>0.05).Conclusions:Diagnosis of fetal intracranial cyst at≤28 weeks gestation and other systemic abnormalities are risk factors affecting pregnancy outcome.

关 键 词：胎儿颅内囊肿 妊娠结局 影响因素 产前诊断 

分 类 号：R714.5[医药卫生—妇产科学]