以手口综合征为唯一临床表现的脑梗死4例临床分析并文献复习  

Clinical analysis of 4 cases of cerebral infarction with cheiro-oral syndrome as the only clinical manifestation and literature review

作　　者：颜谈 张艳[1] 王国防 刘璐 王幼萌[1] YAN Tan;ZHANG Yan;WANG Guofang;LIU Lu;WANG Youmeng(Department of Neurology,Fuyang People's Hospital,Fuyang People's Hospital Affiliated to Anhui Medical University,Fuyang,Anhui 236000,China)

机构地区：[1]阜阳市人民医院、安徽医科大学附属阜阳人民医院神经内科,安徽阜阳236000

出　　处：《安徽医药》2025年第1期166-169,共4页Anhui Medical and Pharmaceutical Journal

基　　金：安徽医科大学校科研基金项目(2022xjk089)。

摘　　要：目的分析4例以手口综合征为唯一临床表现的脑梗死的疾病特点,提高大家对该综合征的认识,避免漏诊、误诊。方法回顾性总结于2021年2月至2022年11月阜阳市人民医院收治的4例以手口综合征为唯一临床表现的脑梗死病人的人口学信息、既往史、临床表现、入院时美国国立卫生研究院卒中量表(NIHSS)评分、缺血性脑卒中病因学分类标准(TOAST)分型、头颅磁共振成像(MRI)所示病变部位、头颈部血管成像、治疗方式及长期预后等资料。结果4例病人均存在至少1种脑梗死高危因素,均表现为同侧口周手部麻木症状,均为腔隙性脑梗死且均为轻型卒中,头颈部血管壁存在斑块或狭窄,给予抗栓、调脂固斑等治疗,2例长期预后留有感觉障碍后遗症,2例无任何后遗症。结论手口综合征最常见于脑梗死病人,该类型脑梗死与其他类型的脑梗死危险因素、TOAST分型、治疗及预后方面存在共性,然而局限性的手口麻木为其特有临床表现。Objective To analyze the characteristics of 4 cases of cerebral infarction with cheiro-oral syndrome as the only clinical manifestation,so as to improve understannding of the syndrome and avoid underdiagnosis and misdiagnosis.Methods The demographic information,previous history,clinical manifestations,NIHSS score on admission,TOAST etiological classification,lesion sites shown in magnetic resonance imaging,head and neck angiography,treatment methods and long-term prognosis of 4 cerebral infarction patients with cheiro-oral syndrome as the only clinical manifestation admitted to Fuyang People´s Hospital from February 2021 to November 2022 were retrospectively summarized.Results All the 4 patients had at least one risk factor for cerebral infarction,symptoms of ipsilateral perioral and hand numbness,lacunar cerebral infarction and mild stroke,with plaque or stenosis in the vascular wall of the head and neck,and were treated with anti-thrombolysis and lipid-controlling plaque fixation.Two cases had sequelae of sensory disturbance in the long term prognosis,and 2 cases had no sequelae.Conclusions Cheiro-oral syndrome is most commonly seen in patients with cerebral infarction.There are similarities between this type of cerebral infarction and other types of cerebral infarction in terms of risk factors,TOAST classification,treatment and prognosis.However,limited cheiro-oral numbness is its unique clinical manifestation.

关 键 词：脑梗死 手口综合征 临床特点 危险因素 治疗 预后 

分 类 号：R743.33[医药卫生—神经病学与精神病学]