依替米星联合左氧氟沙星治疗急性细菌性感染性腹泻的效果分析  

Analysis of the Effect of Etimicin Combined with Levofloxacin in the Treatment of Acute Bacterial Infectious Diarrhea

作　　者：曲燕燕 Qu Yanyan(Department of Infectious Diseases,Aviation General Hospital,Beijing 100012,China)

机构地区：[1]航空总医院感染疾病科,北京100012

出　　处：《中外医药研究》2024年第31期48-50,共3页JOURNAL OF CHINESE AND FOREIGN MEDICINE AND PHARMACY RESEARCH

摘　　要：目的:分析依替米星联合左氧氟沙星治疗急性细菌性感染性腹泻的临床效果。方法:选取2021年1月—2023年8月航空总医院收治的100例急性细菌性感染性腹泻患者为研究对象,随机分成对照组和观察组,各50例。对照组采用依替米星治疗,观察组在对照组基础上增加左氧氟沙星治疗。对比两组治疗有效率、症状缓解时间、血常规白细胞与大便常规转阴率、不良反应及治疗满意度。结果:观察组治疗有效率高于对照组(P=0.001);观察组腹痛缓解时间、腹泻缓解时间、发热缓解时间、呕吐缓解时间短于对照组(P<0.05);观察组血常规白细胞与大便常规转阴率均高于对照组(P<0.05);两组不良反应发生率对比,无统计学差异(P>0.05);观察组治疗满意度高于对照组(P=0.003)。结论:依替米星联合左氧氟沙星治疗急性细菌性感染性腹泻的效果较好,可以有效缓解患者的临床症状,提高患者的治疗满意度,安全性较高。Objective:To analyze the clinical effect of etimicin combined with levofloxacin in the treatment of acute bacterial infectious diarrhea.Methods:One hundred patients with acute bacterial infectious diarrhea admitted to the Aviation General Hospital from January 2021 to August 2023 were selected as the study subjects,and randomly divided into the control group and the observation group,fifty cases each.The control group was treated with etimicin,and the observation group was treated with levofloxacin added to the control group.The two groups were compared in terms of treatment efficiency,symptom relief time,conversion rate of blood leukocytes and stool routine,adverse reactions and treatment satisfaction.Results:The treatment efficiency of the observation group was higher than that of the control group(P=0.001);the relief time of abdominal pain,diarrhea,fever and vomiting was shorter than that of the control group(P<0.05);the conversion rate of blood leukocytes and stool routine of the observation group was higher than that of the control group(P<0.05);and the incidence rate of adverse reactions of the two groups was compared with that of the control group,and there was no statistically significant difference(P>0.05);the treatment satisfaction of the observation group was higher than that of the control group(P=0.003).Conclusion:Etimicin combined with levofloxacin is effective in the treatment of acute bacterial infectious diarrhea,which can effectively alleviate the clinical symptoms of patients,improve the treatment satisfaction of patients,and has a high degree of safety.

关 键 词：左氧氟沙星 急性细菌性感染性腹泻 依替米星 

分 类 号：R574.62[医药卫生—消化系统]