硬腭黏膜修补缺损联合皮瓣移植在眼睑恶性肿瘤手术切除中的应用效果  

Effectiveness of Hard Palate Mucosal Repair Defect Combined with Flap Grafting in Surgical Excision of Eyelid Malignant Tumors

作　　者：罗序香 Luo Xuxiang(Huaian Jinhu County Hospital of Traditional Chinese Medicine,Huaian 211600,Jiangsu Province,China)

机构地区：[1]淮安市金湖县中医院,江苏淮安211600

出　　处：《中外医药研究》2024年第32期25-27,共3页JOURNAL OF CHINESE AND FOREIGN MEDICINE AND PHARMACY RESEARCH

摘　　要：目的:探讨硬腭黏膜修补缺损联合皮瓣移植用于眼睑恶性肿瘤患者切除术后眼睑重建的效果。方法:选取2015年9月—2024年2月于淮安市金湖县中医院行手术切除治疗的眼睑恶性肿瘤患者78例作为研究对象,采用随机数字表法分为观察组与对照组,每组39例。两组均接受眼睑恶性肿瘤切除手术,对照组行皮瓣移植手术,观察组行硬鄂黏膜修补缺损联合皮瓣移植手术。比较两组睑裂长度及高度差值、修复效果、并发症发生情况及生活质量评分。结果:修复后,两组睑裂长度、高度差值均小于修复前,观察组小于对照组(P<0.05);观察组修复总有效率高于对照组(P<0.05);观察组并发症总发生率低于对照组(P=0.042);修复后,两组情绪功能、角色功能、认知功能、躯体功能评分均高于修复前,观察组高于对照组(P<0.05)。结论:眼睑恶性肿瘤患者手术切除后应用硬鄂黏膜修补缺损联合皮瓣移植,可有效减小睑裂的长度、高度差值,减少并发症,提高生活质量,提高整体疗效。Objective:To investigate the effect of hard palate mucosal repair defect combined with flap grafting for eyelid reconstruction after excision in patients with eyelid malignant tumor.Methods:Seventy-eight cases of patients with eyelid malignant tumors who underwent surgical excision treatment in Huaian Jinhu County Hospital of Traditional Chinese Medicine from September 2015 to February 2024 were selected as the study subjects,and were divided into the observation group and the control group by using the random number table method,with thirty-nine cases in each group.Both groups underwent eyelid malignant tumor excision surgery,the control group underwent flap grafting surgery,and the observation group underwent hard palate mucosal repair defect combined with flap grafting surgery.The difference in the length and height of the eyelid fissure,the effect of repair,the occurrence of complications and the quality of life scores were compared between the two groups.Results:After repair,the difference in the length and height of the blepharospasm of the two groups was smaller than that before repair,and the observation group was smaller than that of the control group(P<0.05);the total effective rate of repair of the observation group was higher than that of the control group(P<0.05);and the total incidence of complications of the observation group was lower than that of the control group(P=0.042);after repair,the scores of emotional functions,role function,cognitive function,and somatic function of both groups were higher than those before repair,and the observation group was higher than the control group(P<0.05).Conclusion:The application of hard palate mucosal repair defect combined with flap grafting after surgical excision of patients with eyelid malignant tumor can effectively reduce the length and height difference of eyelid fissure,reduce the complications,improve the quality of life,and enhance the overall therapeutic efficacy.

关 键 词：皮瓣移植 硬腭黏膜修补缺损 手术切除 眼睑恶性肿瘤 

分 类 号：R739.71[医药卫生—肿瘤]