Development of a MaizeGerm50K array and application to maize genetic studies and breeding  

作　　者：Honghui Guan Yaxuan Lu Xinchun Li Bei Liu Yongxiang Li Dengfeng Zhang Xuyang Liu Guanhua He Yu Li Hongwu Wang Tianyu Wang Chunhui Li 

机构地区：[1]State Key Laboratory of Crop Gene Resources and Breeding,Institute of Crop Sciences,Chinese Academy of Agricultural Sciences,Beijing 100081,China

出　　处：《The Crop Journal》2024年第6期1686-1696,共11页作物学报（英文版）

基　　金：supported by grants from Scientific Innovation 2030 Project (C.W,2022ZD0401703);National Key Research and Development Program of China (2021YFD1200700);National Natural Science Foundation of China (32372082);China Agriculture Research System (CARS-02-03);Innovation Program of Chinese Academy of Agricultural Sciences.

摘　　要：Genotyping arrays based on single nucleotide polymorphisms(SNPs)provide a low-cost,highthroughput platform.The development of a SNP array that fully reflects the genetic diversity of maize(Zea mays L.)germplasm and is applicable to molecular breeding programs is desirable.In this study,we developed a MaizeGerm50K array comprising 50,852 SNPs selected from the resequencing data of 1604 maize inbred lines and other markers.A genome-wide association study using a landrace panel genotyped with the array permitted mapping of several known genes.We also verified a candidate gene,RNA-binding motif protein 24-like 1(ZmRBM24L1),delaying flowering through overexpression lines.Genomic selection for yield and agronomic traits showed high prediction accuracy.The MaizeGerm50K array is thus a valuable genomic tool for maize genetic studies and breeding.

关 键 词：MAIZE GENOTYPING Liquid array Single nucleotide polymorphism(SNP) Molecular breeding 

分 类 号：S513[农业科学—作物学]