GENOTYPING

作品数：256被引量：823H指数：13
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相关机构：复旦大学上海市卫生健康委员会南京农业大学中国农业大学更多>>
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A high-resolution 20K SNP array for comprehensive genotyping and genetic mapping in Nicotiana tabacum L.
《The Crop Journal》2025年第2期630-635,共6页Shizhou Yu Zhixiao Yang Jie Zhang Linggai Cao Jie Liu Peng Lu Jiemeng Tao Jufen Wan Qingdong Zeng Tenghang Xu Peijian Cao Jingjing Jin Xueliang Ren 
supported by the Guizhou Provincial Basic Research Program(Natural Science)[(2024)648];the Program of China National Tobacco Corporation(110202101032(JY-09),110202201003(JY-03));the Program of Guizhou Branch of China National Tobacco Corporation(2023XM02,2021XM05,2022XM05,2024XM01).
Nicotiana tabacum(2n=4x=48),an economically important non-food crop and a model plant for genetic studies,faces challenges in efficient genotyping of novel germplasm.To address this,we developed the Ta-LD-SC,a 20K SNP...
关键词：Cultivated tobacco SNP array Population structure Differentiation patterns Breeding and genetic improvement 
Genotypic Distribution of the Human Papillomavirus among Women with Cervical Cytological Abnormalities at the Sourô SANOU University Hospital in Bobo-Dioulasso, Burkina Faso
《American Journal of Molecular Biology》2025年第1期11-24,共14页Pierre Zabré Tani Sagna Valentin Konsegre Alioun Traore Sylvie Tuina Astrid Sana Abdou Azaque Zouré Wendkuuni Florencia Djigma Isabelle Tiendrebeogo Prosper Bado Tampoubila Edwige Yelemkoure Madeleine Kabre Kadari Cisse Albert T. Yonli Henri Gautier Ouedraogo Jacques Simporé 
Cervical cancer is the fourth most common cancer worldwide, accounting for 6.8% of new cancer cases and 8.1% of cancer-related deaths. About 85% of these deaths occurred in low- and middle-income countries. The aim of...
关键词：GENOTYPING Human Papillomavirus Cervical Cytological Abnormalities Burkina Faso 
Development of a MaizeGerm50K array and application to maize genetic studies and breeding
《The Crop Journal》2024年第6期1686-1696,共11页Honghui Guan Yaxuan Lu Xinchun Li Bei Liu Yongxiang Li Dengfeng Zhang Xuyang Liu Guanhua He Yu Li Hongwu Wang Tianyu Wang Chunhui Li 
supported by grants from Scientific Innovation 2030 Project (C.W,2022ZD0401703);National Key Research and Development Program of China (2021YFD1200700);National Natural Science Foundation of China (32372082);China Agriculture Research System (CARS-02-03);Innovation Program of Chinese Academy of Agricultural Sciences.
Genotyping arrays based on single nucleotide polymorphisms(SNPs)provide a low-cost,highthroughput platform.The development of a SNP array that fully reflects the genetic diversity of maize(Zea mays L.)germplasm and is...
关键词：MAIZE GENOTYPING Liquid array Single nucleotide polymorphism(SNP) Molecular breeding 
RNA SNP Detection Method With Improved Specificity Based on Dual-competitive-padlock-probe
《生物化学与生物物理进展》2024年第11期3021-3033,共13页ZHANG Qin-Qin LI Jin-Ze ZHANG Wei LI Chuan-Yu ZHANG Zhi-Qi YAO Jia DU Hong ZHOU Lian-Qun GUO Zhen 
国家重点研发计划(2023YFC2413202);国家自然科学基金(82372142,52275581,82327802);江苏省重点研发项目(BE2022739);中国科学院青年创新促进会(Y2022088);中国科学院仪器开发项目(ZDKYYO20210004);苏州市科技发展项目(SJC2021019,SSD2023012,SSD2023017)资助。
Objective The detection of RNA single nucleotide polymorphism(SNP)is of great importance due to their association with protein expression related to various diseases and drug responses.At present,splintR ligase-assist...
关键词：RNA single nucleotide polymorphism GENOTYPING rolling circle amplification dual padlock probe 
Streamlined whole-genome genotyping through NGS-enhanced thermal asymmetric interlaced(TAIL)-PCR
《Plant Communications》2024年第9期25-37,共13页Sheng Zhao Yue Wang Zhenghang Zhu Peng Chen Wuge Liu Chongrong Wang Hong Lu Yong Xiang Yuwen Liu Qian Qian Yuxiao Chang 
supported by the Science and Technology Planning Project of Guangdong Province(2022B0202060002);the National Natural Science Foundation of China(32300340,32172086);the R&D program of Shenzhen(KCXFZ20211020164207012);the R&D Program in Key Areas of Guangdong Province(2021B0707010006);ACKNOWLEDGMENTS We thank Lili Dong(China National Center for Bioinformation/Beijing Institute of Genomics,Chinese Academy of Sciences)for assistance with uploading the raw sequencing data.Y.C.,S.Z.,P.C.,et al.are listed as co-inventors on a patent application(CN202211418)。
Whole-genome genotyping(WGG)stands as a pivotal element in genomic-assisted plant breeding.Nevertheless,sequencing-based approaches for WGG continue to be costly,primarily owing to the high expenses associated with li...
关键词：whole-genome genotyping primer-template mismatched annealing specific primer arbitrary degenerate primer molecular breeding 
Utility of next-generation sequencing for the etiological diagnosis of Orientia tsutsugamushi infection
《Infectious Medicine》2024年第3期10-16,共7页Nannan Xu Lintao Sai Gang Wang Gregory A.Dasch Marina E.Eremeeva 
Background Scrub typhus,an acute febrile disease caused by Orientia tsutsugamushi,is transmitted to humans through infected chigger mites.We present a case of scrub typhus in a previously healthy man from Shandong Pro...
关键词：Orientia tsutsugamushi Next-generation sequencing GENOTYPING Scrub typhus Shandong Province China Laboratory diagnosis 
Genotyping on circulating tumor DNA improves mutation detection rate in high-risk diffuse large B-cell lymphoma
《Genes & Diseases》2024年第4期116-119,共4页Yi Xia Li Wang Jinhua Liang Haorui Shen Jiazhu Wu Hua Yin Yue Li Huayuan Zhu Jianyong Li Wei Xu 
supported by the National Natural Science Foundation of China(No.81700193,81770166,82170186,81720108002);Jiangsu Province's Medical Elite Programme of China(No.ZDRCA2016022);Project of National Key Clinical Specialty of China,Jiangsu Provincial Special Program of Medical Science of China(No.BE2017751);National Science and Technology Major Project of China(No.2018ZX09734007);China Postdoctoral Science Foundation(No.2021M691336);Jiangsu Postdoctoral Science Foundation of China(No.2021K083A).
Diffuse large B-cell lymphoma(DLBCL)is the most common lymphoma with heterogeneous clinical outcomes.Patients who are primarily refractory to the frontline therapy or relapse less than 12 months after diagnosis have a...
关键词：LYMPHOMA diagnosis clinical 
Prostate cancer genotyping for risk stratification and precision treatment
《Current Urology》2024年第2期87-97,共11页Ashish A.Kumar 
Prostate cancer(PC)is the most frequently diagnosed cancer and second leading cause of cancer-related deaths in men.It is heterogeneous,as is evident from the wide spectrum of therapeutic approaches.Most patients with...
关键词：Prostate cancer Prostate cancer treatment Prostate cancer genomics Hereditary prostate cancer Androgen deprivation therapy Hormone sensitive prostate cancer Kinase signaling 
Early and Sensitive Detection of Pathogens for Public Health and Biosafety:An Example of Surveillance and Genotyping of SARS-CoV-2 in Sewage Water by Cas12a-Facilitated Portable Plasmonic Biosensor
《Research》2024年第2期259-272,共14页Tianzhong Li Yuzhi Chen Zhi Chen Yuan Hao Minyi Liang Yingxia Liu Guanyong Ou Huanian Zhang Yuxuan Tang Yabing Hao Swelm Wageh Omar AAl-Hartomy Abul Kalam Bin Zhang Xin Shi Xuejin Li Han Zhang 
supported by the National Natural Science Foundation of China(no.U1813207);the State Key Research Development Program of China(no.YS2022YFB3200011);Stabilization Support Program for Higher Education Institutions of Shenzhen(no.20200812115548001);Shenzhen Bay Laboratory Open Fund Project(no.SZBL2021080601012);High-end Talent Scientific Research Startup Project(no.827-000636);Shenzhen Science and Technology R&D and Innovation Foundation(no.JCJY20200109105608771);The authors acknowledge the support and funding of King Khalid University through Research Center for Advanced Materials Science(RCAMS)under grant no.RCAMS/KKU/0010/21.
Infectious diseases severely threaten public health and global biosafety.In addition to transmission through the air,pathogenic microorganisms have also been detected in environmental liquid samples,such as sewage wat...
关键词：fiber consuming hinder 
CRISPR genotyping and regional distribution characteristics of Yersinia pestis in natural plague focus of Tibet Autonomous Region
《China Medical Abstracts(Internal Medicine)》2024年第2期88-88,共1页杨晓艳 
Objective Tostudy the clustered regularly interspaced short palindromic repeats(CRISPR)genotype of Yersinia pestis and its regional distribution characteristics in natural plaguefocusofTibet Autonomous Region.Methods ...
关键词：CRISPR distribution characteristics 
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