不同海拔高度对人体睡眠及认知功能的影响  

Effects of different altitudes on sleep and cognitive function

作　　者：刘晓钰 王云英 路志红 LIU Xiaoyu;WANG Yunying;LU Zhihong(Department of Anesthesiology and Perioperative Medicine,Xijing Hospital,Air Force Medical University,Xi'an 710032,China)

机构地区：[1]空军军医大学西京医院麻醉与围术期医学科,陕西西安710032

出　　处：《空军军医大学学报》2024年第12期1464-1468,共5页Journal of Air Force Medical University

基　　金：国家自然科学基金重点科学基金(81871028)。

摘　　要：高海拔地区的低压低氧环境是诱发睡眠障碍和认知功能障碍的主要危险因素,而不同海拔高度对睡眠和认知的影响不同。海拔越高,对机体睡眠和认知的影响越大,随着海拔的增加,导致睡眠期间频繁觉醒和呼吸暂停,总睡眠时间和慢波睡眠减少,进而导致睡眠效率低下。同时高海拔地区会造成学习、记忆、执行力和注意力等认知功能受损。高海拔地区导致的睡眠障碍和认知功能缺损是相互关联并相互作用的,同时其发生和发展的机制尚不明确,因此未来的研究应更加关注高海拔地区睡眠障碍和认知障碍发生的关键机制,并寻找新的有效治疗方法。Hypobaric hypoxic environment at high altitudes is a major risk factor for inducing sleep disorders and cognitive dysfunction,and the effects on sleep and cognition vary at different altitudes.Higher altitudes have a greater impact on sleep and cognition.With increasing altitude,individuals experience frequent awakenings and apnea during sleep,resulting in a decrease in total sleep time and slow wave sleep and ultimately leading to sleep inefficiency.High altitudes can have negative effects on cognitive functions such as learning,memory,executive power,and attention.Sleep disorders and cognitive impairments caused by high altitudes are interrelated and interact with each other,and their mechanism of occurrence and development is still unclear.Therefore,future research should pay more attention to the key mechanisms of sleep disorders and cognitive impairments at high altitudes and explore new effective treatments.

关 键 词：高海拔 低氧 睡眠 认知 

分 类 号：R740[医药卫生—神经病学与精神病学]