经直肠超声联合IPSAD在前列腺癌早期诊断中的应用  

Application of transrectal ultrasound combined with IPSAD in early diagnosis of prostate cancer

作　　者：王丽娟 曹小宁 Wang Lijuan;Cao Xiaoning(Tangshan Central Hospita)

机构地区：[1]唐山中心医院

出　　处：《现代科学仪器》2024年第6期268-272,共5页Modern Scientific Instruments

摘　　要：目的:探讨经直肠超声(TRUS)+内腺区特异性抗原密度(IPSAD)对前列腺癌(PCa)早期诊断价值。方法:以我院2022年6月~2023年12月收治的PCa患者87例为PCa组,取同期收治的良性前列腺增生(BPH)患者87例为BPH组,均行TRUS+IPSAD评估,分析其对PCa的诊断效能。结果:PCa组前列腺边界不清晰、内外腺边界不清晰、异常血流信号、低回声结节占比高于BPH组(P<0.05)。PCa组内腺区体积低于BPH组,前列腺特异性抗原(PSA)、IPSAD高于BPH组(P<0.05)。TRUS+IPSAD诊断PCa的曲线下面积(AUC)为0.955,高于TRUS的0.816及IPSAD的0.872(P<0.05)。TRUS+IPSAD诊断PCa的特异度、准确率、阳性预测值高于TRUS、IPSAD(P<0.05)。结论:TRUS声像特征+IPSAD能提高PCa诊断的特异度、准确率、阳性预测值。Objective To investigate the value of transrectal ultrasound(TRUS)combined with inner gland region prostate specific antigen density(IPSAD)in the early diagnosis of prostate cancer(PCa)..Methods A total of 87 patients with PCa admitted to our hospital from June 2022 to December 2023 were selected as the PCa group,and 87 patients with benign prostatic hyperplasia(BPH)admitted during the same period were selected as the BPH group.TRUS combined with IPSAD was evaluated to analyze its diagnostic efficacy for PCa.Results The proportion of unclear prostatic boundary,unclear internal and external gland boundary,abnormal blood flow signal and low echo nodule in PCa group was higher than that in BPH group(P<0.05).The volume of gland area in PCa group was lower than that in BPH group,and prostate specific antigen(PSA)and IPSAD in BPH group were higher than those in BPH group(P<0.05).The area under curve(AUC)of TRUS combined with IPSAD was 0.955,which was higher than that of TRUS(0.816)and IPSAD(0.872)(P<0.05).The specificity,accuracy and positive predictive value of TRUS combined with IPSAD in the diagnosis of PCa were higher than those of TRUS and IPSAD(P<0.05).Conclusion TRUS features combined with IPSAD can improve the specificity,accuracy and positive predictive value of PCa diagnosis.

关 键 词：前列腺癌 经直肠超声 内腺区特异性抗原密度 曲线下面积 诊断价值 

分 类 号：R730.41[医药卫生—肿瘤]