大肠侧向发育型肿瘤分型中蓝光成像与化学染色技术应用  

Application of blue light imaging and chemical staining techniques in the classification of laterally spreading tumor of the large intestine

作　　者：许家珂 赵坚敏 蔡丽莉 Xu Jiake;Zhao Jianmin;Cai Lili(Gastroenterology Department of Kunshan Second People's Hospital,Suzhou 215300,Jiangsu)

机构地区：[1]昆山市第二人民医院消化内科,江苏苏州215300

出　　处：《现代科学仪器》2024年第6期316-321,共6页Modern Scientific Instruments

摘　　要：目的:探究亮蓝光成像模式(BLI-bright)联合化学染色技术在大肠侧向发育型肿瘤(LST)分型中的诊断价值。方法:选取2021年1月-2024年1月收治的LST的150例(168处病变)患者,行BLI-bright联合化学染色技术检查,比较和术后病理结果一致性。结果:BLI-bright+化学染色分型:各类型肿瘤的诊断灵敏度介于50.00%(ⅢS型对SMd)至90.68%(ⅢL型、Ⅳ型对LGD/HGD),特异度在78.00%(ⅢL型、Ⅳ型)至98.75%(ⅢS型)间。联合诊断时,灵敏度和特异度分别可达100.00%和96.88%,整体准确度91.67%-97.02%,AUC 0.741-0.984,Kappa 0.512-0.747。结论:BLI-bright联合化学染色技术能准确展现LST的Pit分型微小结构,具备肿瘤良恶性判断的高临床应用价值。Objective:To investigate the diagnostic value of blue light imaging(BLI-bright)combined with chemical staining techniques in the classification of lateral spreading tumor(LST)of the large intestine.Methods:150 patients(with 168 lesions)diagnosedwith LST admitted from January 2021 to January 2024,and performed BLI-bright combined with chemical staining technique examination.We compared the consistency between the results and postoperative pathological findings.Results:BLI-bright+chemical staining typing:The diagnostic sensitivity for various types of tumors ranged from 50.00%(type III S vs.SMd)to 90.68%(types III L and IV vs.LGD/HGD),with specificity ranging from 78.00%(types III L and IV)to 98.75%(type III S).When combined with diagnosis,the sensitivity and specificity could reach 100.00%and 96.88%,respectively,with overall accuracy ranging from 91.67%to 97.02%,AUC ranging from 0.741 to 0.984,and Kappa ranging from 0.512 to 0.747.Conclusion:BLI-bright combined with chemical staining technology can accurately reveal the Pit-type microstructure of LST,which holds high clinical application value in determining the benign or malignant nature of tumors.

关 键 词：亮蓝光成像 化学染色技术 大肠侧向发育型肿瘤 分型 

分 类 号：R574.6[医药卫生—消化系统]