黄鳝雄激素受体生物信息学分析  

Bioinformatics Analysis of Androgen Receptor in Monopterus albus

作　　者：凌智 杨文林 袁汉文[1,2] LING Zhi;YANG Wen-lin;YUAN Han-wen(Yangtze University,Jingzhou,Hubei 434025;Hubei Province Monopterus albus Technology Research Center,Jingzhou,Hubei 434025)

机构地区：[1]长江大学,湖北荆州434025 [2]湖北省黄鳝工程技术研究中心,湖北荆州434025

出　　处：《安徽农业科学》2024年第24期80-85,136,共7页Journal of Anhui Agricultural Sciences

基　　金：国家现代农业产业技术体系资助项目(CARS-46)。

摘　　要：为了进一步研究黄鳝(Monopterus albus)雄激素受体的结构与功能,利用生物信息学方法对黄鳝雄激素受体的理化性质与空间结构进行了预测。结果表明,黄鳝雄激素受体基因全长2774 bp,完整开放阅读框2238 bp,可以编码746个氨基酸。M.albus AR蛋白的分子量为83.71 ku,为酸性亲水的不稳定蛋白质,不具有信号肽和跨膜区域,不属于分泌蛋白。该蛋白有72个可能的磷酸化位点。该蛋白二级结构以α-螺旋和无规则卷曲为主。In order to further study the structure and function of the androgen receptor in the eel(Monopterus albus),bioinformatics methods were used to predict the physicochemical properties and spatial structure of M.albus AR.The results showed that M.albus AR gene had a total length of 2774 bp,a complete open reading frame of 2238 bp,and it could encode 746 amino acids.The molecular weight of M.albus AR protein was 83.71 ku,it was an acidic and hydrophilic unstable protein.It had no signal peptides or transmembrane regions and it was not a secreted protein.This protein had 72 possible phosphorylation sites.The second structure of this protein was mainlyα-helix and random coil.

关 键 词：黄鳝 雄激素受体 生物信息学分析 

分 类 号：S966.4[农业科学—水产养殖]