宫颈癌背部软组织转移一例  

A Case of Soft Tissue Metastasis in the Back from Cervical Cancer

作　　者：宋翰 刘晗黎 王希波[2] SONG Han;LIU Han-li;WANG Xi-bo(School of Clinical Medicine,Shandong Second Medical University,Weifang 261000,Shandong Province,China;Department of Gynecology,The First Affiliated Hospital of Shandong Second Medical University,Weifang People's Hospital,Weifang 261000,Shandong Province,China)

机构地区：[1]山东第二医科大学临床医学院,山东省潍坊市261000 [2]山东第二医科大学第一附属医院(潍坊市人民医院)妇科

出　　处：《国际妇产科学杂志》2024年第6期672-675,691,共5页Journal of International Obstetrics and Gynecology

基　　金：山东省医药卫生科技发展计划项目(202105010306)。

摘　　要：宫颈癌是全球女性第四大常见癌症,常见远处转移部位包括肺、骨、肝脏、脑,软组织转移十分罕见。其软组织转移临床表现通常为质硬、界不清、活动差的肿块,伴疼痛、麻木和肌力减退。报告1例已婚女性,同房后阴道出血1个月余,经宫颈活检确诊为宫颈鳞状细胞癌。2023年8月排除手术禁忌后,于全身麻醉下行根治性子宫切除术+盆腔淋巴结切除术+腹主动脉旁淋巴结切除术,术后行化疗联合放疗。术后5个月发现左侧背部皮下肿物,活检提示为鳞状细胞癌,考虑宫颈来源。考虑疾病出现进展,行骨骼肌软组织肿瘤根治性切除术,更改治疗方案为放疗、免疫治疗联合紫杉醇类与铂类药物化疗。截至末次随访时间,患者病情稳定。宫颈癌的软组织转移较为罕见,临床症状往往并不明显,早期诊断对患者的预后至关重要。Cervical cancer is the fourth most common cancer among women in the world,with common sites of distant metastasis including the lungs,bones,liver,and brain,Metastasis to soft tissues is very rare.The clinical manifestations of soft tissue metastasis typically present as hard,ill-defined,and poorly mobile masses accompanied by pain,numbness,and muscle weakness.We report a case of a married woman who presented with vaginal bleeding after sexual intercourse for more than a month and was diagnosed with cervical squamous cell carcinoma via cervical biopsy.In August 2023,after excluding surgical contraindications,she underwent radical hysterectomy,pelvic lymph node dissection,and paraortic lymph node dissection under general anesthesia,followed by postoperative chemotherapy combined with radiotherapy.Five months postoperatively,a subcutaneous mass was found on the left side of the back,and biopsy revealed squamous cell carcinoma,suggesting a cervical origin.Given the progression of the disease,radical resection of the skeletal muscle soft tissue tumor was performed,and the treatment regimen was changed to radiotherapy,immunotherapy,combined with chemotherapy using paclitaxel and platinum--based drugs.As of the last follow-up,the patient's condition was stable.Soft tissue metastasis of cervical cancer is rare,and the clinical symptoms are often not obvious.Early diagnosis is crucial for the prognosis of patients.

关 键 词：宫颈肿瘤 肿瘤转移 软组织肿瘤 背 病例报告 

分 类 号：R737.33[医药卫生—肿瘤]