高频重复经颅磁刺激对脑卒中后偏瘫患者上肢运动功能的临床效果  

Clinical Effect of High-Frequency Repetitive Transcranial Magnetic Stimulation on Upper Limb Motor Function in Patients with Hemiplegia after Stroke

作　　者：姚恩平 黄旭明[1] 张其明 单莎瑞[1] YAO Enping;HUANG Xuming;ZHANG Qiming;SHAN Sharui(Department of Rehabilitation,The First Affiliated Hospital of Guangdong Pharmaceutical University,Guangzhou 510699,China)

机构地区：[1]广东药科大学附属第一医院康复科,广东广州510699

出　　处：《反射疗法与康复医学》2024年第14期37-39,47,共4页Reflexology And Rehabilitation Medicine

基　　金：广东药科大学2023年度本科教学质量与教学改革工程项目(202333);2024年度广东省医学科研基金立项项目(B2024222)。

摘　　要：目的探讨高频重复经颅磁刺激对脑卒中后偏瘫患者上肢体运动功能的效果。方法选取2020年9月—2021年11月广东药科大学附属第一医院收治的50例脑卒中后偏瘫患者为研究对象,按随机数字表法将其分为试验组和对照组,各25例。两组在常规康复治疗的基础上,试验组采用5 Hz的重复经颅磁刺激患侧M1区治疗,对照组采用经颅磁伪刺激治疗。对比两组的运动诱发电位波幅、握力值及上肢运动功能。结果治疗后,两组运动诱发电位波幅、握力值均大于治疗前,且试验组均大于对照组,两组Fugl-Meyer运动功能评定量表上肢部分评分均高于治疗前,且试验组Fugl-Meyer运动功能评定量表上肢部分评分为(37.04±11.26)分,高于对照组的(31.00±9.69)分,差异有统计学意义(P<0.05)。结论患侧M1区高频重复经颅磁刺激治疗脑卒中偏瘫患者,有利于提高运动诱发电位幅度,改善其上肢运动功能。Objective To investigate the effect of high-frequency repetitive transcranial magnetic stimulation on upper limb motor function in patients with hemiplegia after stroke.Methods Fifty patients with post-stroke hemiplegia admitted to the First Affiliated Hospital of Guangdong Pharmaceutical University from September 2020 to November 2021 were selected as the research objects,and were divided into a experimental group and a control group according to random number table method,with 25 cases in each group.On the basis of conventional rehabilitation treatment,the experimental group was treated with 5 Hz repeated transcranial magnetic stimulation of the M1 area on the affected side,and the control group was treated with transcranial magnetic pseudo-stimulation.Motor evoked potential amplitude,grip strength and upper limb motor function were compared between the two groups.Results After treatment,the motor evoked potential amplitude and grip strength of both groups were higher than those before treatment,and the experimental group were higher than those in the control group,the Fugl-Meyer Assessment-Upper Extremities score in both groups was higher than those before treatment,and the Fugl-Meyer Assessment-Upper Extremities score in the experimental group was(37.04±11.26)points,which was higher than(31.00±9.69)points of the control group,and the differences were statistically significant(P<0.05).Conclusion High-frequency repetitive transcranial magnetic stimulation in the M1 region of the affected side can improve the amplitude of motor evoked potentials and improved the motor function of the upper limbs of stroke patients with hemiplegia.

关 键 词：脑卒中 高频重复经颅磁刺激 上肢运动功能 

分 类 号：R743.3[医药卫生—神经病学与精神病学]