山东省淄博市某医院2023年过敏性疾病患者过敏原检测结果分析  

Analysis of Allergen Detection Results of Patients with Allergic Diseases in 2023 in a Hospital in Zibo City,Shandong Province

作　　者：曹程 薛钧予 杨继霞 徐慧 赵峰 CAO Cheng;XUE Jun-yu;YANG Ji-xia;XU Hui;ZHAO Feng(Department of Clinical Laboratory,Zibo Municipal Hospital,Zibo Shandong 255400,China)

机构地区：[1]淄博市市立医院检验科,山东淄博255400

出　　处：《中华养生保健》2024年第23期92-96,共5页CHINESE HEALTH CARE

基　　金：山东省青年自然科学研究课题(2024年度)(24ZRK027)。

摘　　要：目的分析山东省淄博市市立医院2023年过敏性疾病患者过敏原检测结果,为本地区过敏性疾病患者的预防和治疗提供参考。方法收集2023年1月—2023年12月就诊于淄博市市立医院的596例过敏性疾病患者血清总IgE(tIgE)和过敏原特异性IgE(sIgE)结果,并根据性别、不同年龄段、月份和疾病进行分组,统计分析tIgE检测值和sIgE阳性率。结果tIgE总阳性率高达52.18%,tIgE在不同性别、年龄、疾病方面差异均有统计学意义(P<0.05)。吸入性过敏原阳性率前3位依次为霉菌混合(点青霉/烟曲霉/交链格孢/枝状枝孢)(32.05%)、户尘螨/粉尘螨(29.87%)、葎草粉(25.00%)。食物性过敏原阳性率前3位依次为海鱼/海蟹(8.39%)、牛奶(6.04%)、大豆(4.70%)。吸入性过敏原检测结果阳性率(17.90%)高于食物性过敏原检测结果阳性率(4.50%),差异有统计学意义(P<0.05)。不同过敏原sIgE、不同性别、年龄、季节、疾病分组比较,差异有统计学意义(P<0.05)。结论调查了淄博地区过敏原tIgE和sIgE的流行特征,有助于本地区过敏性疾病的诊断和防治。Objective To analyze the detection results of patients with allergic diseases in 2023 in a hospital in Zibo city,Shandong province,and to provide reference for the prevention and treatment of patients with allergic diseases in this area.Methods A total of 596 patients with allergic diseases admitted to Zibo Municipal Hospital from January 2023 to December 2023 were collected,and serum total IgE and allergen specifi c IgE(sIgE)results were extracted from all patients,and grouped according to gender,diff erent age groups,months and diseases,and total IgE detection values and sIgE positive rates were statistically analyzed.Results The total positive rate of total IgE was 52.18%,there were significant differences in total IgE among different sex,age and disease groups(P<0.05).The top 3 positive rates of inhalation allergens were fungal mixture(penicillium punctata/Aspergillus fumigatus/cladosporium alternativa/cladosporium cladosporium)(32.05%),household dust mite/Dermatophagoides culinae(29.87%)and Myrtle powder(25.00%).The top 3 positive rates of food allergens were Sea fi sh/sea crab(8.39%),milk(6.04%)and soybean(4.70%).The positive rate of inhalation allergen detection(17.90%)was higher than that of food allergen detection(4.50%),the diff erence was statistically signifi cant(P<0.05).There were statistically signifi cant diff erences among diff erent allergens in diff erent gender,age,season and disease groups(P<0.05).Conclusion The epidemiological characteristics of total IgE and sIgE in Zibo area were investigated,which is helpful for the diagnosis and prevention of allergic diseases in this area.

关 键 词：过敏性疾病 过敏原 TIGE 过敏原特异性IGE 吸入性过敏原 食物性过敏原 

分 类 号：R593.1[医药卫生—内科学]