Supported by Youth Project of Guangxi International Zhuang Medicine Hospital,No.[2022]203;Discipline Project of Guangxi International Zhuang Medicine Hospital,No.[2021]33;Research Fund of Guangxi International Zhuang Medicine Hospital,No.RCYJ202201.
BACKGROUND Colorectal cancer(CRC)remains one of the most common malignancies worldwide,with a significant subset of patients exhibiting absence of carcinoembryonic-antigen(CEA)expression.The lack of effective diagnost...
Despite existing curative options like surgical removal,tissue destruction techniques,and liver transplantation for early-stage hepatocellular carcinoma(HCC),the rising incidence and mortality rates of this global hea...
supported by grants from the National Natural Science Foundation.The project was supported by the Major International(Regional)Joint Research Program of China(Grant No.82020108005);the Science Fund for Outstanding Young Scholars of China(Grant No.82022008).
Background:Pancreatic ductal adenocarcinoma(PDAC)is one of the main types of malignant tumor of the digestive system,and patient prognosis is affected by difficulties in early diagnosis,poor treatment response,and a h...
support from New York University Abu Dhabi(NYUAD)Faculty Research.Fund(AD266)。
Dendritic cells(DCs)play a pivotal role in bridging the innate and adaptive immune systems.From their immature state,scavenging tissue for foreign antigens to uptake,then maturation,to their trafficking to lymph nodes...
supported by the National Key Research and Development Program of China (2023YFC2307800);Chengdu University of Traditional Chinese Medicine (030040018);Shanghai Municipal Science and Technology Major Project (ZD2021CY001);National Natural Science Foundation of China (32270142);Shanghai Rising-Star Program (22QA1408800)。
Currently approved vaccines have been successful in preventing the severity of COVID-19 and hospitalization. These vaccines primarily induce humoral immune responses;however, highly transmissible and mutated variants,...
Neutrophils,the most abundant white blood cells in the human body,have long been recognized for their critical role in innate immunity(Quail et al.,2022).They serve as the first line of defense against invading pathog...
supported by grants from the Double First-Class Project from the Ministry of Education(grant code:WF510162602);Innovative Research Team of High-Level Local Universities in Shanghai,Shanghai Collaborative Innovation Program on Regenerative Medicine and Stem Cell Research(grant code:2019CXJQ01);Overseas Expertise Introduction Project for Discipline Innovation(111 Project;grant code:B17029);National Natural Science Foundation of China(grant numbers:82230006 and 81900206);Shanghai Shenkang Hospital Development Center(grant code:SHDC2020CR5002);Shanghai Frontiers Science Center for Biomacromolecules and Precision Medicine-ShanghaiTech University,Shanghai Pilot Program for Basic Research-Shanghai Jiao Tong University(grant code:21TQ1400226).
Ligand-induced receptor dimerization or oligomerization is a widespread mechanism for ensuring communication specificity,safeguarding receptor activation,and facilitating amplification of signal transduction across th...