TIGE

作品数:177被引量:579H指数:13
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相关领域:医药卫生更多>>
相关作者:孙宝清朱晓萍韦妮莉黄惠敏魏庆宇更多>>
相关机构:贵州医科大学广州医科大学广州呼吸疾病研究所贵阳医学院附属医院更多>>
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相关基金:国家自然科学基金国家重点基础研究发展计划北京市自然科学基金广东省自然科学基金更多>>
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Value of brief hematological characteristics in differentiating carcinoembryonic-antigen-negative colorectal cancer from benign colorectal diseases
《World Journal of Gastrointestinal Surgery》2025年第2期145-153,共9页Li-Ling Yi Xian-Jun Lao Liu-Yi Lu Chun-Ling Zhu Dong-Yi Zhou Si-Ting Li Meng-Li Fan Qi-Liu Peng 
Supported by Youth Project of Guangxi International Zhuang Medicine Hospital,No.[2022]203;Discipline Project of Guangxi International Zhuang Medicine Hospital,No.[2021]33;Research Fund of Guangxi International Zhuang Medicine Hospital,No.RCYJ202201.
BACKGROUND Colorectal cancer(CRC)remains one of the most common malignancies worldwide,with a significant subset of patients exhibiting absence of carcinoembryonic-antigen(CEA)expression.The lack of effective diagnost...
关键词:Hematological parameters Carcinoembryonic-antigen-negative Colorectal cancer Biomarkers Inflammatory cell ratios 
Immunotherapy and liver transplantation for hepatocellular carcinoma:Current and future challenges
《World Journal of Transplantation》2025年第2期8-29,共22页Theodoros Pettas Sofia Lachanoudi Filippos F Karageorgos Ioannis A Ziogas Asimina Fylaktou Vassilios Papalois Georgios Katsanos Nikolaos Antoniadis Georgios Tsoulfas 
Despite existing curative options like surgical removal,tissue destruction techniques,and liver transplantation for early-stage hepatocellular carcinoma(HCC),the rising incidence and mortality rates of this global hea...
关键词:Hepatocellular carcinoma IMMUNOTHERAPY Liver transplantation Neoadjuvant and adjuvant immunotherapy Immune checkpoint inhibitors Vaccine therapies Oncolytic viruses Adoptive cell therapy Antigen-targeting antibodies Diagnostic biomarkers 
“Relative symmetry with electronegativity of different key-groups” strategy for MRGPRX2 antagonist design and its effect on antigeninduced pulmonary inflammation
《Acta Pharmaceutica Sinica B》2025年第1期494-507,共14页Jiayu Lu Zhaomin Xia Yongjing Zhang He Wang Wen Yang Siqi Wang Nan Wang Yun Liu Huaizhen He Cheng Wang Langchong He 
supported by the National Natural Science Foundation of China(grant Nos.81930096 and 82373830).
MRGPRX2 antagonists possess the potential for the treatment of allergic rhinitis,atopic dermatitis,and chronic urticaria.Previously,we identified a class of diaryl urea(DPU)MRGPRX2 antagonists with sub-micromolar IC50...
关键词:MRGPRX2 ANTAGONIST Diaryl urea Relative symmetrywith electronegativity Antiallergicactivity Antigen-induced pulmonary inflammation Structure-activity relationships Electrostatic 
山东省淄博市某医院2023年过敏性疾病患者过敏原检测结果分析
《中华养生保健》2024年第23期92-96,共5页曹程 薛钧予 杨继霞 徐慧 赵峰 
山东省青年自然科学研究课题(2024年度)(24ZRK027)。
目的分析山东省淄博市市立医院2023年过敏性疾病患者过敏原检测结果,为本地区过敏性疾病患者的预防和治疗提供参考。方法收集2023年1月—2023年12月就诊于淄博市市立医院的596例过敏性疾病患者血清总IgE(tIgE)和过敏原特异性IgE(sIgE)结...
关键词:过敏性疾病 过敏原 TIGE 过敏原特异性IGE 吸入性过敏原 食物性过敏原 
FeNO和TIgE及外周血EOS计数联合检测对儿童2型气道炎症相关咳嗽变异性哮喘的诊断价值
《中国妇幼健康研究》2024年第11期76-84,共9页赵苗苗 陈露萍 杨轶童 马文娟 孙媛 孙珠君 石曌玲 
国家自然科学基金青年科学基金项目(82205188);咸阳市科技局重点研发计划(2021ZDYF-SF-0043)。
目的探讨呼出气一氧化氮(FeNO)、总免疫球蛋白E(TIgE)及外周血嗜酸性粒细胞(EOS)计数联合检测对儿童2型气道炎症相关咳嗽变异性哮喘(CVA)的诊断价值。方法收集2022年12月至2023年8月在陕西中医药大学第二附属医院行FeNO、过敏原及外周血...
关键词:儿童 一氧化氮 免疫球蛋白E 嗜酸性粒细胞 咳嗽变异性哮喘 2型气道炎症 
Single-cell RNA sequencing reveals the process of CA19-9 production and dynamics of the immune microenvironment between CA19-9 (+) and CA19-9 (−) PDAC
《Chinese Medical Journal》2024年第20期2415-2428,共14页Deyu Zhang Fang Cui Kailian Zheng Wanshun Li Yue Liu Chang Wu Lisi Peng Zhenghui Yang Qianqian Chen Chuanchao Xia Shiyu Li Zhendong Jin Xiaojiang Xu Gang Jin Zhaoshen Li Haojie Huang 
supported by grants from the National Natural Science Foundation.The project was supported by the Major International(Regional)Joint Research Program of China(Grant No.82020108005);the Science Fund for Outstanding Young Scholars of China(Grant No.82022008).
Background:Pancreatic ductal adenocarcinoma(PDAC)is one of the main types of malignant tumor of the digestive system,and patient prognosis is affected by difficulties in early diagnosis,poor treatment response,and a h...
关键词:Carbohydrate antigen 19-9 CA19-9 Pancreatic ductal adenocarcinoma Single-cell RNA sequencing M2 macrophages Antigen-presenting cancer-associated fibroblast 
Tug of war:Understanding the dynamic interplay of tumor biomechanical environment on dendritic cell function
《Mechanobiology in Medicine》2024年第3期7-21,共15页Brian Chesney Quartey Gabriella Torres Mei ElGindi Aseel Alatoom Jiranuwat Sapudom Jeremy C.M Teo 
support from New York University Abu Dhabi(NYUAD)Faculty Research.Fund(AD266)。
Dendritic cells(DCs)play a pivotal role in bridging the innate and adaptive immune systems.From their immature state,scavenging tissue for foreign antigens to uptake,then maturation,to their trafficking to lymph nodes...
关键词:Dendritic cells MECHANOBIOLOGY Biomechanical cues Antigen uptake Antigen presentation Immunotherapy 
TIgE、SIgE与梅尼埃病患者前庭功能损害的相关性
《河南医学研究》2024年第15期2804-2808,共5页王季 张建 王凯 
目的分析血清总免疫球蛋白E(TIgE)、特异性免疫球蛋白E(SIgE)与梅尼埃病患者前庭功能的相关性。方法将2021年3月至2023年2月门诊收治的67例梅尼埃病患者为观察组,同期50例入院体检健康者为对照组,检测两组血清TIgE、SIgE,以及纯音听阈...
关键词:梅尼埃病 血清总免疫球蛋白E 特异性免疫球蛋白E 前庭功能 
Development of T cell antigen-based human coronavirus vaccinesagainst nAb-escaping SARS-CoV-2 variants被引量:1
《Science Bulletin》2024年第15期2456-2470,共15页Hao Zhou Ping Leng Yang Wang Kaiwen Yang Chen Li David M.Ojcius Pengfei Wang Shibo Jiang 
supported by the National Key Research and Development Program of China (2023YFC2307800);Chengdu University of Traditional Chinese Medicine (030040018);Shanghai Municipal Science and Technology Major Project (ZD2021CY001);National Natural Science Foundation of China (32270142);Shanghai Rising-Star Program (22QA1408800)。
Currently approved vaccines have been successful in preventing the severity of COVID-19 and hospitalization. These vaccines primarily induce humoral immune responses;however, highly transmissible and mutated variants,...
关键词:COVID-19 Immune escape Omicron variant SARS-CoV-2 T cell antigen-based vaccine 
Unleashing the power of antigen-presenting neutrophils
《Journal of Molecular Cell Biology》2024年第6期59-60,共2页Yingcheng Wu Jiaqiang Ma Qiang Gao 
Neutrophils,the most abundant white blood cells in the human body,have long been recognized for their critical role in innate immunity(Quail et al.,2022).They serve as the first line of defense against invading pathog...
关键词:NEUTROPHILS IMMUNITY POWER 
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