Studies on nutritional intervention of ginkgo starch-lauric acid complex in obese rats induced by a high-fat diet  

作　　者：Dan Li Xinyue Zhang Xiangxing Meng Nan Zhang Jing Li Tianxin Wang Shan Gao Suwen Liu Jilite Wang Hao Wang 

机构地区：[1]State Key Laboratory of Food Nutrition and Safety,Tianjin University of Science and Technology(TUST),Tianjin,300457,China [2]College of Bioscience and Bioengineering,Hebei University of Science and Technology,Shijiazhuang,050000,China [3]College of Food Science and Technology,Hebei Normal University of Science and Technology,Qinhuangdao,Hebei,066004,China [4]Department of Agriculture,Hetao College,Inner Mongolia,Bayannur,China

出　　处：《Food Bioscience》2023年第3期1594-1602,共9页食品生物科学（英文）

基　　金：supported by the National Natural Science Foundation of China(NO.32101952).

摘　　要：Ginkgo starch was frequently used in food,but consuming too much of it could increase postprandial blood sugar and potentially cause obesity.Through molecular docking,we discovered that lauric acid enters the spiral cavity formed by amylose molecules to form a stable compound.The compound exhibited a V-type structure,enhanced relative crystallinity,short-range order,and long-range order,while also experiencing a 20%reduction in in vitro digestibility.The complex may also lessen body weight,serum triglyceride(TG)and total cholesterol(TC)levels in rats,as well as improve hepatic fat accumulation and intestinal flora composition.It’s interesting to note that the complex greatly boosted the number of good bacteria in rats,and that these bacteria positively connected with the production of short-chain fatty acids(SCFAS),superoxide dismutase(SOD),TC,and TG.In conclusion,the high-fat diet-induced obesity is significantly improved by the ginkgo starch-lauric acid combination(GSL).

关 键 词：Ginkgo starch Fatty acid Intestinal flora Biochemical indices Obese rats 

分 类 号：TS201.4[轻工技术与工程—食品科学]