Phytochemical analysis,mineral composition,Assessment of antioxidant properties and cytotoxic potential of Ephedra alata.subsp.Alenda secondary metabolites  

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作  者:Katia Belazougui Samir Mesrouk Hichem Mohammedi Selma Akcha Lynda Aïnouz Samira Faiza Mecherara-Idjeri 

机构地区:[1]Laboratory of Functional Organic Analysis,Faculty of Chemistry,University of Sciences and Technology Houari Boumediene(USTHB),Bab Ezzouar Algiers,Algeria [2]Laboratory of Electrochemistry-Corrosion,Metallurgy and Mineral,Chemistry Faculty of Chemistry,University of Sciences and Technology Houari Boumediene(USTHB),016111,Bab Ezzouar-Algiers,Algeria [3]University of Sciences and Technology Houari Boumediene(USTHB),Laboratory of Hydrometallurgy and Molecular Inorganic Chemistry Faculty of Chemistry,16111,Bab Ezzouar-Algiers,Algeria [4]Faculty of Veterinary Medicine,Higher National Veterinary School ENSV,16059,Oued Smar-Algiers,Algeria [5]Laboratory of Biology and Animal Physiology,ENS,16308,Kouba-Algiers,Algeria

出  处:《Food Bioscience》2023年第3期1720-1728,共9页食品生物科学(英文)

摘  要:A study of the phytocomposition of Ephedra alata susbp.alenda Trab is here presented.In the essential oil,mainly predominate oxygenated terpenoids such as thymol,cumal and anethole.A chemical screening revealed a high rate of alkaloids,tannins,flavonoids and quinones.In order to optimize the extraction of these compounds,three methods and five solvents have been used,and according to this,the aqueous extract obtained by Soxhlet contained the highest value of polyphenol,whereas alkaloids were best extracted by isopropanol.Some mineral elements were quantified by ED-XRF and AAS analysis to assess a potential toxicity due to overdose in comparison with the daily-recommended doses.All extracts showed strong antioxidant activity,especially the ethanolic fraction.The haemolysis behaviour of Ephedra is considered as slightly toxic.The in vivo evaluation of the acute toxicity led to the absence of lethality.However,anomalies were observed and correlated with the compositions of the extracts.

关 键 词:Ephedra alata susbp.alenda Trab Essential oil POLYPHENOLS Haemolysis activity Acute toxicity Trace element 

分 类 号:TS201[轻工技术与工程—食品科学]

 

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