Impact of the microbiome on human,animal,and environmental health from a One Health perspective  

作　　者：Ling-chao Ma Han-qing Zhao Logan Blair Wu Zi-le Cheng Chang Liu 

机构地区：[1]School of Global Health,Chinese Centre for Tropical Diseases Research,Shanghai Jiao Tong University School of Medicine,Shanghai,China [2]One Health Centre,Shanghai Jiao Tong University and the University of Edinburgh,Shanghai,China [3]Department of Immunology and Microbiology,Shanghai Jiao Tong University School of Medicine,Shanghai,China [4]Population Health&Immunity Division,Walter and Eliza Hall Institute of Medical Research,Parkville,Melbourne,Australia [5]Department of Medical Biology,University of Melbourne,Melbourne,Australia

出　　处：《Science in One Health》2023年第1期24-33,共10页全健康科学（英文）

摘　　要：The microbiome encompasses the genomes of the microorganisms that inhabit specific environments.One Health is an emerging concept,recognised as a cohesive,harmonising approach aimed at sustainably improving the well-being of humans,animals,and the environment.The microbiome plays a crucial role in the One Health domain,facilitating interactions among humans,animals,and the environment,along with co-evolution,co-development,co-metabolism,and co-regulation with their associated humans and animals.In addition,the microbiome regulates environmental health through interactions with plant microbiota,which actively participate in substance cycling(particularly the carbon and nitrogen cycles)and influence the overall energy flow in the biosphere.Moreover,antibiotic resistance genes present in microbiota can lead to widespread drug resistance in both humans and animals.This review explores the impact of the microbiome on humans,animals,and the environment,highlighting the significance of focusing on this field in One Health research.

关 键 词：One Health MICROBIOME CO-EVOLUTION Substance cycling 

分 类 号：TG1[金属学及工艺—金属学]