牙周-正畸联合治疗慢性牙周炎患者的临床疗效及其预后的影响因素  

Clinical Efficacy of Periodontal-Orthodontic Combined Treatment in Patients with Chronic Periodontitis and Factors Influencing Prognosis

作　　者：王书英 李静[1] WANG Shuying;LI Jing(Department of Periodontology,Anyang Sixth People's Hospital,Anyang Henan 455000,China)

机构地区：[1]安阳市第六人民医院牙周病科,河南安阳455000

出　　处：《临床研究》2025年第1期72-75,共4页Clinical Research

摘　　要：目的探究在牙周基础治疗同时增加正畸治疗对慢性牙周炎患者的临床疗效及其预后的影响因素。方法回顾性分析2021年3月至2023年3月安阳市第六人民医院牙周病科收治的慢性牙周炎患者(146例)的临床资料,按照治疗方法不同分为A组(65例)与B组(81例),A组进行牙周基础治疗,B组进行牙周基础治疗+正畸治疗。对比两组治疗后6个月临床疗效,治疗前及治疗后6个月牙龈指数、牙周袋深度、肿瘤坏死因子-α、白细胞介素-6水平。治疗后6个月根据牙周袋深度将B组患者(81例)分为预后不良组(牙周袋深度≥4 mm,31例)、预后良好组(牙周袋深度<4 mm,50例),分析患者临床资料,将患者临床病历资料信息开展多因素Logistic回归分析,识别并量化影响患者牙周-正畸联合治疗效果及预后的关键因素。结果B组治疗有效率(96.30%)高于A组,差异具有统计学意义(P<0.05);治疗后6个月,两组牙龈指数、牙周袋深度、肿瘤坏死因子-α、白细胞介素-6水平均降低,且B组低于A组,差异均有统计学意义(P<0.05);单因素结果显示,预后不良组患者患牙为下颌牙、前牙、根型态异常占比均高于预后良好组,差异均有统计学意义(P<0.05);经多元Logistic回归分析结果得出,患牙为下颌牙、前牙、根型态异常是影响慢性牙周炎患者牙周-正畸联合治疗预后的影响因素(P<0.05)。结论牙周基础治疗同时增加正畸治疗对慢性牙周炎患者临床效果较好,可改善牙周指数、降低炎症反应。患牙为下颌牙、前牙、根型态异常是影响患者治疗预后不良的影响因素,临床需对以上患者进行密切关注,并采取针对性措施。Objective To investigate the clinical efficacy and prognostic factors of combined orthodontic treatment alongside basic periodontal therapy in patients with chronic periodontitis.Methods A retrospective analysis was conducted on the clinical data of 146 chronic periodontitis patients treated at the Department of Periodontology of Anyang Sixth People's Hospital from March 2021 to March 2023.Patients were divided into two groups based on treatment Methods Group A(65 patients)received basic periodontal treatment,while Group B(81 patients)received basic periodontal treatment combined with orthodontic treatment.After 6 months,the two groups were compared regarding clinical efficacy,plaque index,probing depth,tumor necrosis factor-alpha,and interleukin-6 levels before and after treatment.Patients in Group B were further divided based on probing depth into a poor prognosis group(depth≥4 mm,31 patients)and a good prognosis group(depth<4 mm,50 patients).Multivariate logistic regression analysis was performed to identify and quantify the key factors influencing the combined treatment outcomes and prognosis.Results The effective treatment rate in Group B(96.30%)was higher than that in Group A,with statistically significant differences(P<0.05).After 6 months,both groups showed reductions in plaque index,probing depth,Tumor necrosis factor-alpha,and Interleukin-6 levels,with Group B showing significantly lower levels than Group A(P<0.05).Univariate analysis indicated that patients in the poor prognosis group had a higher proportion of mandibular teeth,anterior teeth,and abnormal root morphology compared to the good prognosis group,with statistically significant differences(P<0.05).Multivariate logistic regression analysis revealed that mandibular teeth,anterior teeth,and abnormal root morphology were significant factors affecting the prognosis of chronic periodontitis patients undergoing combined periodontal-orthodontic treatment(P<0.05).Conclusion Adding orthodontic treatment to basic periodontal therapy significantly enha

关 键 词：正畸治疗 牙周治疗 慢性牙周炎 临床疗效 预后 影响因素 

分 类 号：R781.42[医药卫生—口腔医学]