靶向胶质瘤微环境的研究进展  

Research advances in targeting glioma microenvironment

作　　者：郑伊桐 米尔阿迪力·阿布力米提 刘文 汪永新[1] ZHENG Yitong;Mieradili·Abulimiti;LIU Wen;WANG Yongxin(Department of Neurosurgery,First Affiliated Hospital of Xinjiang Medical University,Urumqi,Xinjiang 830000,China)

机构地区：[1]新疆医科大学第一附属医院神经外科,乌鲁木齐830000

出　　处：《重庆医学》2024年第24期3815-3820,共6页Chongqing Medical Journal

基　　金：新疆维吾尔自治区科学技术厅自然科学基金重点项目(2022D01D70)。

摘　　要：胶质瘤作为一种高度复杂和致命的脑肿瘤,其治疗一直是神经外科和肿瘤学领域的重大挑战。近年来,对胶质瘤微环境的深入研究为理解其发病机制和开发新的治疗策略提供了新的视角。该文介绍了胶质瘤微环境的主要组成、调控的信号通路和可能的治疗靶点,旨在提供一个全面的视角来理解和治疗这种复杂的肿瘤,强调了胶质瘤微环境在胶质瘤研究和治疗中的重要性。Glioma serves as a highly complex and lethal brain tumor,its treatment has been a major challenge in neurosurgery and oncology.In recent years,the in-depth studies of glioma microenvironment have provided new perspectives for understanding its pathogenesis and developing new therapeutic strategies.This article introduces the major components of glioma microenvironment,regulation signaling pathways and possible therapeutic targets,aiming to provide a comprehensive perspective to understand and treat this complex tumor and emphasizing the importance of the glioma microenvironment in glioma research and treatment.

关 键 词：神经系肿瘤 微环境 治疗 

分 类 号：R739.4[医药卫生—肿瘤]