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作 者:陈敬予 王少丽[1] 李游[1] 赵迎盼 姜天童[1] 田志华 刘震 CHEN Jing-yu;WANG Shao-li;LI You;ZHAO Ying-pan;JIANG Tian-tong;TIAN Zhi-hua;LIU Zhen(Guang'anmen Hospital,China Academy of Chinese Medical Sciences,Beijing,100053,China;Xiyuan Hospital,China Academy of Chinese Medical Sciences,Beijing,100091,China;Beijing University of Chinese Medicine,Beijing,100029,China)
机构地区:[1]中国中医科学院广安门医院,北京100053 [2]中国中医科学院西苑医院,北京100091 [3]北京中医药大学,北京100029
出 处:《现代生物医学进展》2024年第22期4243-4246,4354,共5页Progress in Modern Biomedicine
基 金:中国中医科学院科技创新工程(CI2021A01010)。
摘 要:目的:基于运气学说探究难治性幽门螺杆菌(Helicobacter pylori,以下简称Hp)感染者出生时运气因素的分布规律及差异性,为Hp感染的防治提供参考依据。方法:通过中国中医科学院西苑医院公众号发放电子问卷,收集2023年7月-2024年4月间符合难治性Hp感染诊断标准的401例患者的一般信息形成病例组,以同时间段就诊于中国中医科学院广安门医院脾胃病科门诊的382例普通型Hp感染患者的一般信息作为对照组,采用Excel建立病例数据库,根据待分析的运气因素对数据进行转化整理,使用SPSS 26.0统计软件进行统计分析。结果:出生在阳明燥金时段,或少阳相火司天、厥阴风木在泉的患者多发展为难治性Hp感染,差异具有统计学意义(P<0.05)。结论:出生年主气为阳明燥金、及出生年为少阳相火司天、厥阴风木在泉的人患难治性Hp感染的风险增加;这类人群需注意顾护脾胃、提高免疫力、恪守良好的生活习惯,一旦感染Hp,需尽快进行规范的根除治疗并及时复查。而出生在主气为少阳相火及太阴湿土时段、或出生年为太阴湿土司天、太阳寒水在泉则罹患难治性Hp的风险降低。Objective:To explore the distribution law and difference of evolutive phases and climatic factors at birth in patients with refractoryHelicobacter pylori(Hp)infection based on Yun-Qi theory.Additionally,we seek to provide reference for the prevention and treatment of Hp infection.Methods:An electronic questionnaire was distributed through the WeChat Official Accounts Platform of Xiyuan Hospital of China Academy of Chinese Medical Sciences to collect general information of 401 patients who met the diagnostic criteria for refractoryHp infection from July 2023 to April 2024 to form a case group.In addition,the medical record data of 382 patients with common Hp infection who were treated in the outpatient department of Spleen and Stomach Diseases,Guang'anmen Hospital,Chinese Academy of Chinese Medical Sciences during the same period was collected as the control group.The case database was established with Excel,the data were transformed and sorted according to the evolutive phases and climatic factors to be analyzed,and statistical software SPSS 26.0 was used for statistical analysis.Results:People born in the Yangming Zaojin period,or in the Shaoyang Xianghuo si-tian,Jueyin Fengmu zai-quan,were more developed refractoryHp infection,the difference was statistically significant(P<0.05).Conclusion:The risk of refractory Hp infection increased when the main-qi was Yangming Zaojin,Shaoyang Xianghuo si-tian,and Jueyin Fengmu zai-quan.These people should pay attention to and protect the spleen and stomach,improve immunity,abide by good living habits.Once infected with Hp,it is necessary to carry out standardized eradication treatment as soon as possible and timely review.The risk of refractoryHp infection was reduced when the main-qi was Shaoyang Xianghuo,Taiyin Shitu si-tian or Taiyang Hanshui zai-quan.
关 键 词:幽门螺杆菌感染 难治性幽门螺杆菌感染 运气学说 五运六气 出生日期
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