胸腹腔镜下食管癌根治术对食管癌患者肺通气功能、炎性反应及免疫功能的影响  

Impact of Thoracoscopic-Laparoscopic Radical Resection of Esophageal Cancer on Pulmonary Ventilation Function,Inflammatory Response and Immune Function of Patients with Esophageal Cancer

作　　者：周大晓 张雪寒[1] ZHOU Daxiao;ZHA NG Xuehan(Department of Cardiothoracic Surgery,the People's Hospital of Tanghe County,Nanyang 473400,China)

机构地区：[1]河南省唐河县人民医院胸心外科,河南南阳473400

出　　处：《临床医学工程》2024年第12期1457-1458,共2页Clinical Medicine & Engineering

摘　　要：目的分析胸腹腔镜下食管癌根治术治疗食管癌患者的临床效果。方法选取我院2020年12月至2022年12月收治的82例食管癌患者,随机分为两组。对照组行开放食管癌根治术,观察组行胸腹腔镜下食管癌根治术。比较两组的肺通气功能、炎性反应、免疫功能。结果术后第7 d,观察组的VC、FEV_(1)、PEF、CD4^(+)均高于对照组,IL-6、CRP水平以及CD8^(+)均低于对照组(P<0.05)。结论胸腹腔镜下食管癌根治术可减轻食管癌患者的炎性反应,改善肺通气功能及免疫功能。Objective To analyze the clinical effect of thoracoscopic-laparoscopic radical resection of esophageal cancer in the treatment of patients with esophageal cancer Methods 82 patients with esophageal cancer admitted to our hospital from December 2020 to December 2022 were selected and randomly divided into two groups.The control group underwent open radical resection of esophageal cancer,and the observation group underwent thoracoscopic-laparoscopic radical resection of esophageal cancer.The pulmonary ventilation function,inflammatory response and immune function were compared between the two groups.Results At the 7^(th)day after surgery,VC,FEV_(1),PEF and CD4^(+)in the observation group were higher than those in the control group,and IL-6 and CRP levels and CD8^(+)were lower than those in the control group(P<0.05).Conclusions Thoracoscopic-laparoscopic radical resection of esophageal cancer can relieve the inflammatory response,and improve pulmonary ventilation function and immune function of patients with esophageal cancer.

关 键 词：胸腹腔镜下食管癌根治术 肺通气功能 炎性反应 免疫功能 

分 类 号：R735.1[医药卫生—肿瘤]