Beyond borders:the choroid plexus-immune communication during neuroinflammation  

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作  者:Anaelle Aurelie Dumas AdriàDalmau Gasull Marco Prinz 

机构地区:[1]Institute of Neuropathology,University of Freiburg,Faculty of Medicine,Freiburg,Germany [2]Signalling Research Centres BIOSS and CIBSS,University of Freiburg,Freiburg,Germany

出  处:《Signal Transduction and Targeted Therapy》2024年第11期4763-4765,共3页信号转导与靶向治疗(英文)

基  金:supported by the Sobek Foundation,the Faber Foundation,the Ernst-Jung Foundation,the DFG(SFB 992,SFB1160,SFB 1479,SFB/TRR167,Reinhart-Koselleck-Grant,Gottfried Wilhelm Leibniz-Prize,Novo-Nordisk Prize);the Ministry of Science,Research and Arts,Baden-Wuerttemberg(Sonderlinie“Neuroinflammation”).

摘  要:In their paper published in Cell,1 Xu et al.leveraged single-cell sequencing and cell lineage tracing tools combined with two-photon live imaging to characterise the spatiotemporal immune recruitment and infiltration to the choroid plexus(ChP).They provide seminal insights into the communication between specialised ChP epithelial and macrophage populations,which coordinate the stepwise response to inflammation and its resolution.

关 键 词:INFLAMMATION PLEXUS 

分 类 号:R392[医药卫生—免疫学]

 

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