海洋糖类化合物与阿尔茨海默病以及帕金森病研究进展  

Research progress on the correlation between Marine carbohydrates and Alzheimer's disease and Parkinson's disease

作　　者：栾同晓 胡松[1] 刘佳[1] 王珊 毛拥军[1] Luan Tongxiao;Hu Song;Liu Jia;Wang Shan;Mao Yongjun(Department of Geriatrics,The Affiliated Hospital of Qingdao University,Qingdao 266003,China)

机构地区：[1]青岛大学附属医院老年医学科,青岛266003

出　　处：《中华老年医学杂志》2024年第12期1657-1660,共4页Chinese Journal of Geriatrics

基　　金：山东省自然科学基金(ZR2021MH197)。

摘　　要：阿尔茨海默病(AD)和帕金森病(PD)是退行性神经系统疾病中发病率最高的两类疾病。海洋糖类化合物因其具有多种生物活性,如抗氧化、抗凝血、抗肿瘤、降血脂、抗菌等,而受到越来越多的关注。目前,海洋糖类化合物在AD和PD中防治发挥作用的相关研究越来越多,本综述总结了海洋糖类化合物在AD和PD作用机制面的研究进展,以期为AD和PD的防治带来新的角度。Alzheimer's disease(AD)and Parkinson's disease(PD)are two of the most prevalent types of degenerative neurological diseases.The biological activities of marine glycoconjugates,such as antioxidant,anticoagulant,antitumor,hypolipidemic,and antibacterial properties,have gained significant attention.There is a growing body of research exploring the role of marine glycoconjugates in AD and PD.This review aims to summarize the recent progress in the use of marine glycoconjugates for the prevention and treatment of AD and PD,providing new insights for future approaches in managing these diseases.

关 键 词：海洋糖类化合物 退行性神经系统疾病 阿尔茨海默病 帕金森病 

分 类 号：R749.16[医药卫生—神经病学与精神病学] R742.5[医药卫生—临床医学]