系统评价与Meta分析中真实世界研究质量评价工具(QATSM-RWS)的解读与应用  

Interpretation and application of the quality assessment tool(QATSM-RWS)for realworld studies in systematic reviews and meta-analysis

作　　者：张强[1] 卢存存 赵文霞[1] 刘鸣昊[1] 闫乐[1] 张丽慧[1] 赵晴 李玲[1] 王思颖 贾攀 尚东方[1] 方进华 ZHANG Qiang;LU Cuncun;ZHAO Wenxia;LIU Minghao;YAN Le;ZHANG Lihui;ZHAO Qing;LI Ling;WANG Siying;JIA Pan;SHANG Dongfang;FANG Jinhua(The First Affiliated Hospital of Henan University of Chinese Medicine,Zhengzhou 450000,P.R.China;Institute of Basic Research in Clinical Medicine,China Academy of Chinese Medical Sciences,Beijing 100700,P.R.China;Jianshi Hospital of Traditional Chinese Medicine,Enshi 445300,P.R.China)

机构地区：[1]河南中医药大学第一附属医院,郑州450000 [2]中国中医科学院中医临床基础医学研究所,北京100700 [3]建始县中医医院,湖北恩施445300

出　　处：《中国循证医学杂志》2024年第12期1451-1457,共7页Chinese Journal of Evidence-based Medicine

基　　金：河南省中医药科学研究专项课题(编号:2024ZY2046);河南省中医学“双一流”创建科学研究专项(编号:STGZYX02-20211T、HSRP-DFCTCM-2023-4-02)。

摘　　要：关注研究质量是现代医学循证实践的重要内容。良好的研究质量是为临床实践提供可靠证据支持的关键。近年来,真实世界研究数量逐渐增多,但因数据质量问题和研究者水平的差异,发表的真实世界研究质量参差不齐。系统评价与Meta分析的结果常作为临床实践决策的重要参考依据,但其研究结果容易受到纳入原始研究的质量影响。基于低质量研究的结果做出的临床决策往往具有一定风险。鉴于目前没有一种专门用于制作系统评价与Meta分析时评价纳入真实世界研究质量的工具,Gebrye团队近期开发了一种新的真实世界研究质量评价工具—QATSM-RWS。该工具包括5个模块,共14个问题导向性评价条目。本文旨在对该工具的制定过程和条目内容进行介绍和解读,并以一项已发表的真实世界研究为例,使用该工具评价其质量,以期为国内研究者应用该工具提供参考和借鉴。Focusing on research quality is a crucial aspect of modern evidence-based medical practice,providing substantial evidence to underpin clinical decision-making.The increase in real-world studies in recent years has presented challenges,with varying quality stemming from issues such as data integrity and researchers’expertise levels.Although systematic reviews and meta-analyses are essential references for clinical decisions,their reliability is contingent upon the quality of the primary studies.Making clinical decisions based on inadequate research poses inherent risks.With the lack of a specialized tool for evaluating the quality of real-world studies within systematic reviews and meta-analyses,the Gebrye team has introduced a new assessment tool-QATSM-RWS.Comprising 5 modules and 14 items,this tool aims to improve real-world research evaluation.This article aims to elaborate on the tool’s development process and content,using this tool to evaluate a published real-world study as an example and providing valuable guidance for domestic researchers utilizing this innovative tool.

关 键 词：真实世界研究 系统评价 META分析 质量评价 工具 代谢相关脂肪性肝病 

分 类 号：R-03[医药卫生]