出 处:《介入放射学杂志》2024年第11期1203-1208,共6页Journal of Interventional Radiology
基 金:江西省卫生健康委科技计划项目(SKJP220210552)。
摘 要:目的对比Azurion全能型大平板造影系统的3D路图技术与普通路图在介入治疗颅内动脉瘤的价值。方法选择2021年2月至2023年5月在赣州市立医院神经外科就诊的颅内动脉瘤患者148例,其中采用3D实时路图治疗的73例为研究组,采用普通路图治疗的75例为对照组。对比两组手术相关指标、栓塞致密程度、图像质量、血清学指标、生活质量,随访6个月,对比两组术后复发率与预后。结果研究组微导管一次塑形到位率高于对照组(P<0.05),研究组术中破裂出血率比对照组低(P<0.05)。研究组手术时间比对照组短(P<0.05),研究组对比剂使用量、机器射线量低于对照组(P<0.05)。研究组Raymond分级分布优于对照组(P<0.05)。研究组图像质量优良率高于对照组(P<0.05)。研究组治疗前后基质金属蛋白酶9(MMP-9)、神经元特异性烯醇化酶(NSE)的差值比对照组高(P<0.05)。研究组治疗前后物质生活、社会功能、心理健康、躯体健康评分的差值比对照组高(P<0.05)。研究组术后复发率比对照组低(P<0.05)。两组格拉斯哥预后量表(GOS)评分比较差异无统计学意义(P>0.05)。结论相比于普通路图,基于Azurion全能型大平板造影系统的3D路图技术应用于颅内动脉瘤介入治疗中效果确切,可缩短手术时间,减少对比剂的使用,降低术中破血出血与术后复发风险,调节血清NSE、MMP-9表达,提高患者生活质量,且预后良好。Objective To compare the application value of Azurion comprehensive large plate imaging system based on 3D road map technology and conventional road map in interventional treatment of intracranial aneurysms.Methods A total of 73 patients with intracranial aneurysms,who received treatment at the Department of Neurosurgery of Ganzhou Municipal Hospital of China from February 2021 to May 2023,were enrolled in this study.The patients were divided into study group(n=73,under the guidance of 3D real-time road map)and control group(n=75,under the guidance of conventional road map).The surgery-related indicators,embolization density,image quality,serological indicators,and quality of life were compared between the two groups.The patients were followed up for 6 months.The recurrence rate and prognosis were compared between the two groups.Results Compared with the control group,in the study group the accurate location rate of microcatheter with single catheterization manipulation was higher(P<0.05),the incidence of intraoperative rupture bleeding was lower(P<0.05),the time spent for operation was shorter(P<0.05),and the amount of the contrast agent used and the machine radiation dose were lower(P<0.05).The Raymond grade distribution in the study group was better than that in the control group(P<0.05).The excellent rate of image quality in the study group was higher than that in the control group(P<0.05).The differences of matrix metalloproteinase 9(MMP-9)and neuron-specific enolase(NSE)before and after treatment in the study group were higher than those in the control group(both P<0.05).The differences of material well-being life,social function,mental health and physical health scores before and after treatment in the study group were higher than those in the control group(all P<0.05).The postoperative recurrence rate in the study group was lower than that in the control group(P<0.05).No statistically significant difference in Glasgow prognostic Scale(GOS)score existed between the two groups(P>0.05).Conclusion Compared wi
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